HitPredict

Interactor 1: CBX4 (O00257)
E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2)
Gene: CBX4

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37071664, 37059091
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 560 Hs			1 1834
+	Hs
		1097412 CBX3_HUMAN (9-163): 8.84e-44: 155: 21.94		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		129677 CBX4_HUMAN (1-560): 7.61e-163: 477: 100.00		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		1129590 CBX2_HUMAN (2-559): 1.2e-82: 269: 23.54		MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56
+	Hs
		854026 CBX3_HUMAN (9-163): 8.84e-44: 155: 21.94		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		853991 CBX1_HUMAN (17-163): 1.9e-39: 144: 21.05		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		1097295 CBX3_HUMAN (9-163): 8.84e-44: 155: 21.94		MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56
+	Hs
		216572 SUV91_HUMAN (4-154): 1.02e-32: 131: 21.15		CABIN_HUMAN (864-1723): 7.69e-09: 63.1: 10.42