Interactor 1: NLRP3 (Q96P20)
NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) (Angiotensin/vasopressin receptor AII/AVP-like) (Caterpiller protein 1.1) (CLR1.1) (Cold-induced autoinflammatory syndrome 1 protein) (Cryopyrin) (PYRIN-containing APAF1-like protein 1)
Gene: NLRP3
Interactor 2: NLRC4 (Q9NPP4)
NLR family CARD domain-containing protein 4 (CARD, LRR, and NACHT-containing protein) (CED-4-like protein Clan) (Caspase recruitment domain-containing protein 12) (Ice protease-activating factor) (Ipaf)
Gene: NLRC4
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15107016 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | NACHT~NACHT, NACHT~NLRC4_HD, NACHT~NLRC4_HD2, NACHT~NOD2_WH, NLRC4_HD~NOD2_WH |
| Common GO terms | GO:0002221 - pattern recognition receptor signaling pathway GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006915 - apoptotic process and 7 others more... |
| Homologous interactions | 18 |
Homologous interactions
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Last updated: 15 Jul 2024
