HitPredict

Interactor 1: FEV (Q99581)
Protein FEV (Fifth Ewing variant protein) (PC12 ETS domain-containing transcription factor 1) (PC12 ETS factor 1) (Pet-1)
Gene: FEV

Interactor 2: HM20B (Q9P0W2)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (BRCA2-associated factor 35) (HMG box-containing protein 20B) (HMG domain-containing protein 2) (HMG domain-containing protein HMGX2) (Sox-like transcriptional factor) (Structural DNA-binding protein BRAF35)
Gene: HMG20B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 238 Hs			1 317
+	Hs
		1304706 FEV_HUMAN (1-238): 7.78e-93: 274: 100.00		HM20A_HUMAN (3-313): 3.45e-57: 189: 46.35
+	Hs
		507513 ERG_HUMAN (3-237): 5.54e-66: 213: 46.86		HM20A_HUMAN (3-313): 3.45e-57: 189: 46.35
+	Hs
		175788 FEV_HUMAN (1-238): 7.78e-93: 274: 100.00		HMGB3_HUMAN (74-137): 6.7e-10: 59.5: 25.76
+	Hs
		507484 ERG_HUMAN (3-237): 5.54e-66: 213: 46.86		SMCE1_HUMAN (74-315): 3.79e-29: 117: 21.18
+	Hs
		507393 ERG_HUMAN (3-237): 5.54e-66: 213: 46.86		SOX10_HUMAN (18-197): 9.55e-29: 116: 16.93
+	Hs
		965419 FLI1_HUMAN (1-237): 3.12e-65: 210: 45.23		SMCE1_HUMAN (74-315): 3.79e-29: 117: 21.18
+	Mm
		818692 ERG_MOUSE (3-237): 1.33e-66: 215: 46.44		SOX2_MOUSE (37-153): 1.1e-26: 109: 26.50
+	Hs
		817932 FLI1_HUMAN (1-237): 3.12e-65: 210: 45.23		SOX2_HUMAN (37-153): 1.65e-26: 108: 24.79
+	Hs
		225727 FLI1_HUMAN (1-237): 3.12e-65: 210: 45.23		SOX15_HUMAN (27-236): 5.03e-27: 107: 14.69
+	Dm
		115536 ETS3_DROME (20-223): 3.68e-56: 188: 48.83		M9PFG6_DROME (8-200): 4.38e-28: 114: 17.35
+	Hs
		542058 ETS1_HUMAN (8-151): 2.42e-54: 182: 46.31		SMCE1_HUMAN (74-315): 3.79e-29: 117: 21.18
+	Mm
		222661 ETS2_MOUSE (10-153): 1.58e-49: 170: 44.83		SMCE1_MOUSE (74-315): 1.95e-27: 112: 21.18
+	Hs
		818085 ELF2_HUMAN (6-234): 6.67e-48: 168: 24.58		SOX2_HUMAN (37-153): 1.65e-26: 108: 24.79
+	Hs
		781159 ETV3_HUMAN (30-193): 7.5e-48: 166: 39.39		SOX2_HUMAN (37-153): 1.65e-26: 108: 24.79
+	Hs
		449519 ETS1_HUMAN (8-151): 2.42e-54: 182: 46.31		HMGB1_HUMAN (64-163): 1.04e-11: 65.3: 25.49
+	Hs
		449582 ETV3_HUMAN (30-193): 7.5e-48: 166: 39.39		HMGB1_HUMAN (64-163): 1.04e-11: 65.3: 25.49