Protein: NSE4A
Non-structural maintenance of chromosomes element 4 homolog A (NS4EA) (Non-SMC element 4 homolog A)

Gene: NSE4A, NSMCE4A
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q9NXX6

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1398162

NSE3
Non-structural maintenance of chromosomes element 3 homolog

7

14

Small-scale

0.967

High

1357657

NSE1
Non-structural maintenance of chromosomes element 1 homolog

5

2

Small-scale

0.930

High

848187

MAGA1
Melanoma-associated antigen 1

2

14

Small-scale

0.776

High

1402677

SMC6
Structural maintenance of chromosomes protein 6

5

11

Small-scale

0.723

High

1313476

SMC5
Structural maintenance of chromosomes protein 5

5

11

Small-scale

0.714

High

1439086

MAGE1
Melanoma-associated antigen E1

1

17

High-throughput

0.691

High

1394959

MAGD4
Melanoma-associated antigen D4

1

17

Small-scale

0.665

High

1405685

NECD
Necdin

1

16

Small-scale

0.665

High

1397727

ZN597
Zinc finger protein 597

4

0

High-throughput

0.661

High

679406

DNJB2
DnaJ homolog subfamily B member 2

3

0

High-throughput

0.638

High

904394

BRCA2
Breast cancer type 2 susceptibility protein

3

0

High-throughput

0.638

High

1413550

IER2
Immediate early response gene 2 protein

3

0

High-throughput

0.638

High

848986

MAGB1
Melanoma-associated antigen B1

1

14

Small-scale

0.618

High

1431426

MAGH1
Melanoma-associated antigen H1

1

16

Small-scale

0.618

High

1452180

MAGC2
Melanoma-associated antigen C2

1

14

Small-scale

0.618

High

1452183

MAGD2
Melanoma-associated antigen D2

1

17

Small-scale

0.618

High

1330838

TSYL6
Testis-specific Y-encoded-like protein 6

2

0

High-throughput

0.602

High

1452184

LMBL1
Lethal(3)malignant brain tumor-like protein 1

2

0

High-throughput

0.602

High

1041801

PPARD
Peroxisome proliferator-activated receptor delta

2

0

High-throughput

0.585

High

1361507

BMAL2
Basic helix-loop-helix ARNT-like protein 2

2

0

High-throughput

0.576

High

1006754

SRPK2
SRSF protein kinase 2

1

1

High-throughput

0.550

High

1402614

SRPK1
SRSF protein kinase 1

1

1

High-throughput

0.550

High

415901

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.518

High

277418

TP4A3
Protein tyrosine phosphatase type IVA 3

1

0

High-throughput

0.513

High

350747

NOE2
Noelin-2

1

0

High-throughput

0.513

High

728628

AKT2
RAC-beta serine/threonine-protein kinase

1

0

High-throughput

0.513

High

960921

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.513

High

1311924

SLF2
SMC5-SMC6 complex localization factor protein 2

1

0

High-throughput

0.513

High

1329907

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.513

High

1353794

HASP
Serine/threonine-protein kinase haspin

1

0

High-throughput

0.513

High

1410837

SLF1
SMC5-SMC6 complex localization factor protein 1

1

0

High-throughput

0.513

High

1420369

TRI31
E3 ubiquitin-protein ligase TRIM31

1

1

Small-scale

0.512

High

167407

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

186073

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

474335

NFIC
Nuclear factor 1 C-type

1

2

High-throughput

0.479

High

1088061

NFIA
Nuclear factor 1 A-type

1

2

High-throughput

0.479

High

1133700

NFIX
Nuclear factor 1 X-type

1

2

High-throughput

0.479

High

1114464

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1452181

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1452182

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

1339857

PJA1
E3 ubiquitin-protein ligase Praja-1

3

0

Small-scale

0.355

High

63323

ODAD3
Outer dynein arm-docking complex subunit 3

3

0

High-throughput

0.347

High

131081

TULP2
Tubby-related protein 2

2

0

High-throughput

0.328

High

1211458

CF141
Uncharacterized protein C6orf141

2

0

High-throughput

0.328

High

1445776

TUFT1
Tuftelin

2

0

High-throughput

0.318

High

289372

CTAG2
Cancer/testis antigen 2

1

0

High-throughput

0.279

Low

300698

KRT37
Keratin, type I cuticular Ha7

1

0

High-throughput

0.279

Low

1178900

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

346416

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.249

Low

1178427

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1407720

EBP2
Probable rRNA-processing protein EBP2

1

0

High-throughput

0.249

Low

1452179

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025