Protein: NSE4
Non-structural maintenance of chromosome element 4 (Non-SMC element 4) (Protein QRI2)

Gene: NSE4
Organism: Saccharomyces cerevisiae S288C
Interactions: 31
UniProt ID: P43124

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0030915 - Smc5-Smc6 complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

845910

SMC5
Structural maintenance of chromosomes protein 5

9

11

Small-scale

0.971

High

845907

NSE3
Non-structural maintenance of chromosome element 3

7

0

Small-scale

0.919

High

845909

NSE1
Non-structural maintenance of chromosomes element 1

4

0

Small-scale

0.845

High

845914

SMC6
Structural maintenance of chromosomes protein 6

5

11

Small-scale

0.706

High

801134

NSE2
E3 SUMO-protein ligase MMS21

5

0

Small-scale

0.681

High

598415

TUP1
General transcriptional corepressor TUP1

2

0

High-throughput

0.541

High

579591

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.516

High

585637

STI1
Heat shock protein STI1

2

1

High-throughput

0.516

High

845904

SSK2
MAP kinase kinase kinase SSK2

2

1

High-throughput

0.516

High

845908

JIP5
WD repeat-containing protein JIP5

1

1

High-throughput

0.515

High

845906

NSE5
Non-structural maintenance of chromosome element 5

1

0

High-throughput

0.513

High

419778

H2A2
Histone H2A.2

1

0

High-throughput

0.493

High

845912

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.493

High

845915

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.493

High

805978

RT107
Regulator of Ty1 transposition protein 107

1

0

Small-scale

0.460

High

707407

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

845913

SMT3
Ubiquitin-like protein SMT3

1

0

Small-scale

0.458

High

392910

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

524297

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526973

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

670848

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

741800

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

811334

CAJ1
Protein CAJ1

1

2

High-throughput

0.445

High

845911

RBX1
RING-box protein HRT1

1

0

High-throughput

0.438

High

545281

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

676095

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

802093

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

2

0

High-throughput

0.295

High

845905

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

2

0

High-throughput

0.295

High

740345

SNQ2
Protein SNQ2

1

0

High-throughput

0.238

Low

626785

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.232

Low

752398

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025