Interactor 1: M3K5 (Q99683)
Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)
Gene: MAP3K5

Interactor 2: CIB1 (Q99828)
Calcium and integrin-binding protein 1 (CIB) (Calcium- and integrin-binding protein) (CIBP) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP) (SNK-interacting protein 2-28) (SIP2-28)
Gene: CIB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.855

The method score is based on:

Property Details
Experiments 19805025, 29644863
Identification Methods pull down, affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~Pkinase
Common GO terms GO:0000287 - magnesium ion binding
GO:0002931 - response to ischemia
GO:0005737 - cytoplasm
GO:0071356 - cellular response to tumor necrosis factor
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1374
Hs

1 191
+ Hs
+ Mm
+ At
+ At
+ At
+ At
+ At
+ Hs
+ At
+ At
+ At
+ Ps
+ Rn
+ At
+ At
+ At
+ At
+ At
+ At
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024