HitPredict - High confidence protein-protein interactions

Interactor 1: LITAF (Q99732)
Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LPS-induced TNF-alpha factor) (Small integral membrane protein of lysosome/late endosome) (p53-induced gene 7 protein)
Gene: LITAF

Interactor 2: LITAF (Q99732)
Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LPS-induced TNF-alpha factor) (Small integral membrane protein of lysosome/late endosome) (p53-induced gene 7 protein)
Gene: LITAF

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.55	0.588

Property	Details
Experiments	36949045, 27927196
Identification Methods	two hybrid, blue native page, nuclear magnetic resonance
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001817 - regulation of cytokine production GO:0005634 - nucleus and 16 others more... GO:0005654 - nucleoplasm GO:0005765 - lysosomal membrane GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0008270 - zinc ion binding GO:0009898 - cytoplasmic side of plasma membrane GO:0010935 - regulation of macrophage cytokine production GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0043231 - intracellular membrane-bounded organelle GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0050699 - WW domain binding GO:0071222 - cellular response to lipopolysaccharide GO:0098559 - cytoplasmic side of early endosome membrane GO:0098560 - cytoplasmic side of late endosome membrane GO:0098574 - cytoplasmic side of lysosomal membrane GO:1901223 - negative regulation of non-canonical NF-kappaB signal transduction
Homologous interactions	0

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Last updated: 15 Jul 2024