Protein: RU2A
U2 small nuclear ribonucleoprotein A' (U2 snRNP A') (Looks exceptionally like U2A protein 1)

Gene: RU2A, LEA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 101
UniProt ID: Q08963

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex
GO:0005686 - U2 snRNP

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

826554

MSL1
U2 small nuclear ribonucleoprotein B''

8

12

Small-scale

0.969

High

1036187

SMD1
Small nuclear ribonucleoprotein Sm D1

6

2

Small-scale

0.943

High

1054391

SMD2
Small nuclear ribonucleoprotein Sm D2

6

3

Small-scale

0.941

High

817176

RSMB
Small nuclear ribonucleoprotein-associated protein B

6

3

Small-scale

0.940

High

1065578

CWC2
Pre-mRNA-splicing factor CWC2

5

5

Small-scale

0.922

High

933152

RUXF
Small nuclear ribonucleoprotein F

5

5

High-throughput

0.912

High

1065582

RUXE
Small nuclear ribonucleoprotein E

5

4

Small-scale

0.908

High

1065587

HSH49
Protein HSH49

5

3

Small-scale

0.906

High

847841

SMD3
Small nuclear ribonucleoprotein Sm D3

4

11

Small-scale

0.886

High

820848

RUXG
Small nuclear ribonucleoprotein G

4

8

Small-scale

0.875

High

1065106

NCBP2
Nuclear cap-binding protein subunit 2

3

2

Small-scale

0.827

High

1028001

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

2

4

Small-scale

0.754

High

1054946

LSM6
LSM complex subunit LSM6

2

5

Small-scale

0.754

High

1037761

CUS1
Cold sensitive U2 snRNA suppressor 1

7

2

Small-scale

0.744

High

739216

PRP19
Pre-mRNA-processing factor 19

6

11

Small-scale

0.729

High

892796

SF3B1
U2 snRNP component HSH155

6

6

Small-scale

0.729

High

1043513

CEF1
Pre-mRNA-splicing factor CEF1

6

4

Small-scale

0.726

High

625142

PRP9
Pre-mRNA-splicing factor PRP9

6

1

Small-scale

0.726

High

743562

RU1A
U1 small nuclear ribonucleoprotein A

2

0

Small-scale

0.716

High

700161

PRP45
Pre-mRNA-processing protein 45

5

2

Small-scale

0.712

High

1047394

RSE1
Pre-mRNA-splicing factor RSE1

5

8

Small-scale

0.710

High

744178

BRR2
Pre-mRNA-splicing helicase BRR2

5

10

Small-scale

0.709

High

751803

PRP8
Pre-mRNA-splicing factor 8

5

4

Small-scale

0.709

High

702289

YJU2
Splicing factor YJU2

5

1

Small-scale

0.706

High

739283

PRP21
Pre-mRNA-splicing factor PRP21

4

1

Small-scale

0.686

High

1044951

SYF1
Pre-mRNA-splicing factor SYF1

4

8

Small-scale

0.686

High

1065584

PRP46
Pre-mRNA-splicing factor PRP46

4

7

Small-scale

0.686

High

638090

ISY1
Pre-mRNA-splicing factor ISY1

4

2

Small-scale

0.683

High

780235

SN114
Pre-mRNA-splicing factor SNU114

4

4

Small-scale

0.676

High

1059212

PRP11
Pre-mRNA-splicing factor PRP11

4

1

Small-scale

0.676

High

1065581

CLF1
Pre-mRNA-splicing factor CLF1

4

12

Small-scale

0.676

High

1053565

SN309
Pre-mRNA-splicing factor SNT309

4

0

Small-scale

0.657

High

664626

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

3

7

Small-scale

0.646

High

796471

SLT11
Pre-mRNA-splicing factor SLT11

3

2

Small-scale

0.640

High

797327

SP381
Pre-mRNA-splicing factor SPP381

3

0

High-throughput

0.634

High

403688

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

High-throughput

0.618

High

818067

LSM4
LSM complex subunit LSM4

1

5

High-throughput

0.618

High

865289

LSM8
LSM2-LSM8 complex subunit LSM8

1

10

High-throughput

0.618

High

924563

LSM7
LSM complex subunit LSM7

1

10

High-throughput

0.618

High

1025661

NAM8
Protein NAM8

1

3

Small-scale

0.618

High

1065577

RU2A
U2 small nuclear ribonucleoprotein A'

1

16

Small-scale

0.618

High

1065579

YRA1
RNA annealing protein YRA1

1

3

High-throughput

0.618

High

1042539

CWC21
Pre-mRNA-splicing factor CWC21

3

0

Small-scale

0.613

High

1044028

CWC15
Pre-mRNA-splicing factor CWC15

3

0

Small-scale

0.613

High

750317

PRP40
Pre-mRNA-processing protein PRP40

2

4

Small-scale

0.584

High

757551

NCBP1
Nuclear cap-binding protein complex subunit 1

2

2

High-throughput

0.584

High

813377

PRP39
Pre-mRNA-processing factor 39

2

8

Small-scale

0.584

High

829965

PRP17
Pre-mRNA-processing factor 17

2

9

High-throughput

0.584

High

1044044

PRP42
U1 small nuclear ribonucleoprotein component PRP42

2

9

Small-scale

0.584

High

1059552

LUC7
Protein LUC7

2

1

Small-scale

0.584

High

945359

LSM3
LSM complex subunit LSM3

1

10

High-throughput

0.575

High

780867

MUD2
Splicing factor MUD2

2

0

Small-scale

0.559

High

797698

NTC20
Pre-mRNA-splicing factor NTC20

2

0

High-throughput

0.559

High

863102

CWC26
Pre-mRNA-splicing factor CWC26

2

0

High-throughput

0.559

High

918232

SNU71
U1 small nuclear ribonucleoprotein component SNU71

2

0

Small-scale

0.559

High

919227

SYF2
Pre-mRNA-splicing factor SYF2

2

0

High-throughput

0.559

High

919737

CWC22
Pre-mRNA-splicing factor CWC22

2

0

High-throughput

0.559

High

1044068

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

2

0

Small-scale

0.559

High

1052786

RU1C
U1 small nuclear ribonucleoprotein C

2

0

Small-scale

0.559

High

1065585

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

2

0

Small-scale

0.559

High

923941

CWC25
Pre-mRNA-splicing factor CWC25

2

0

High-throughput

0.547

High

635995

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

2

1

High-throughput

0.537

High

917502

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

6

High-throughput

0.536

High

1055566

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.513

High

444647

DED1
ATP-dependent RNA helicase DED1

1

4

High-throughput

0.479

High

590228

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

7

High-throughput

0.479

High

625055

PRP6
Pre-mRNA-splicing factor 6

1

11

High-throughput

0.479

High

627875

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

1

6

High-throughput

0.479

High

638021

PRP5
Pre-mRNA-processing ATP-dependent RNA helicase PRP5

1

4

Small-scale

0.479

High

672083

BUD31
Pre-mRNA-splicing factor BUD31

1

2

High-throughput

0.479

High

694665

SPT5
Transcription elongation factor SPT5

1

2

Small-scale

0.479

High

708445

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

738937

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

1

High-throughput

0.479

High

914888

CWC23
Pre-mRNA-splicing factor CWC23

1

4

High-throughput

0.479

High

1030600

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.479

High

1038499

CWC27
Peptidyl-prolyl isomerase CWC27

1

2

High-throughput

0.479

High

1057304

RDS3
Pre-mRNA-splicing factor RDS3

1

1

High-throughput

0.479

High

1065580

BBP
Branchpoint-bridging protein

1

2

Small-scale

0.479

High

501747

YSF3
RDS3 complex subunit 10

1

0

High-throughput

0.458

High

781592

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.458

High

797801

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

805649

LSM12
Protein LSM12

1

0

High-throughput

0.458

High

886360

PRP31
Pre-mRNA-processing factor 31

1

0

High-throughput

0.458

High

919449

PBP1
PAB1-binding protein 1

1

0

High-throughput

0.458

High

922182

PAP2
Poly(A) RNA polymerase protein 2

1

0

Small-scale

0.458

High

923147

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.458

High

1026952

PRP38
Pre-mRNA-splicing factor 38

1

0

High-throughput

0.458

High

1038543

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.458

High

1042459

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

1

0

High-throughput

0.458

High

1042842

EBS1
Nonsense-mediated mRNA decay factor EBS1

1

0

High-throughput

0.458

High

1055003

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.458

High

1065583

SNU23
23 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1065586

BRR1
Pre-mRNA-splicing factor BRR1

1

0

High-throughput

0.458

High

628240

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

7

High-throughput

0.437

High

812737

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

824806

MLP2
Protein MLP2

1

14

High-throughput

0.437

High

1046077

DHR1
Probable ATP-dependent RNA helicase DHR1

1

6

High-throughput

0.437

High

676441

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

924514

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

826225

FAF1
Protein FAF1

1

0

Small-scale

0.409

High


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Last updated: 11Aug2025