Interactor 1: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Interactor 2: TLR8 (Q9NR97)
Toll-like receptor 8 (CD antigen CD288)
Gene: TLR8

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.34 0.60 0.457

The method score is based on:

Property Details
Experiments 16482509
Identification Methods two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0010008 - endosome membrane
GO:0016064 - immunoglobulin mediated immune response
GO:0032731 - positive regulation of interleukin-1 beta production
GO:0032755 - positive regulation of interleukin-6 production
and 5 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 296
Hs

1 1041
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024