HitPredict

Interactor 1: PSDE (O00487)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)
Gene: PSMD14

Interactor 2: PSMD7 (P51665)
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)
Gene: PSMD7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 25416956, 26186194, 28514442, 32296183, 33961781, 19615732, 26496610, 27428775, 28821611, 28292943, 35530310, 35235311, 37071682, 20656689, 17323924, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, pull down, cross-linking study, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~JAB, JAB~MitMem_reg
Common GO terms GO:0000502 - proteasome complex
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 310
Hs

1 324
+ Dm
+ Sp
+ Ce
+ Sc
+ Hs
+ Mm
+ Hs
+ Dm
+ At
+ At
+ At
+ At
+ At
+ Zm
+ Zm
+ An
+ Ce
+ Hs
+ At
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024