HitPredict

Interactor 1: ARP5L (Q9BPX5)
Actin-related protein 2/3 complex subunit 5-like protein (Arp2/3 complex 16 kDa subunit 2) (ARC16-2)
Gene: ARPC5L

Interactor 2: ARP3B (Q9P1U1)
Actin-related protein 3B (ARP3-beta) (Actin-like protein 3B) (Actin-related protein ARP4)
Gene: ACTR3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.900

Property	Details
Experiments	24981860, 28514442, 17353931, 33961781
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~P16-Arc
Common GO terms	GO:0005737 - cytoplasm GO:0051015 - actin filament binding GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 153 Hs			1 418
+	Hs
		181357 ARPC5_HUMAN (1-153): 1.65e-66: 200: 68.18		ARP3B_HUMAN (1-418): 0: 590: 100.00
+	Hs
		896810 ARP5L_HUMAN (1-153): 1.54e-71: 213: 100.00		ARP3_HUMAN (1-418): 0: 571: 90.67
+	Hs
		181310 ARPC5_HUMAN (1-153): 1.65e-66: 200: 68.18		ARP3_HUMAN (1-418): 0: 571: 90.67
+	Dm
		689669 Q9VQD8_DROME (1-149): 3.62e-62: 189: 48.67		ARP3_DROME (1-418): 0: 557: 79.67
+	Hs
		891995 ARP5L_HUMAN (1-153): 1.54e-71: 213: 100.00		ACTB_HUMAN (1-414): 0: 528: 35.42
+	Hs
		929987 ARP5L_HUMAN (1-153): 1.54e-71: 213: 100.00		ACTG_HUMAN (1-414): 0: 528: 35.18
+	Hs
		181314 ARPC5_HUMAN (1-153): 1.65e-66: 200: 68.18		ACTG_HUMAN (1-414): 0: 528: 35.18
+	Sc
		775027 ARPC5_YEAST (6-153): 4.52e-51: 161: 29.03		ARP3_YEAST (6-417): 2.6e-173: 493: 57.46