Protein: MBIP1
MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein)

Gene: MBIP1, MBIP
Organism: Homo sapiens
Interactions: 181
UniProt ID: Q9NS73

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0004860 - protein kinase inhibitor activity
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

903542

WDR5
WD repeat-containing protein 5

10

2

Small-scale

0.759

High

1333492

CSR2B
Cysteine-rich protein 2-binding protein

9

3

High-throughput

0.758

High

1290302

SGF29
SAGA-associated factor 29

7

1

Small-scale

0.748

High

266435

TAD2A
Transcriptional adapter 2-alpha

6

3

Small-scale

0.730

High

267707

TADA3
Transcriptional adapter 3

6

2

Small-scale

0.730

High

1271456

KAT2A
Histone acetyltransferase KAT2A

6

4

Small-scale

0.730

High

1345376

YETS2
YEATS domain-containing protein 2

6

2

Small-scale

0.730

High

1223197

ZZZ3
ZZ-type zinc finger-containing protein 3

5

1

High-throughput

0.714

High

1271504

KAT2B
Histone acetyltransferase KAT2B

5

4

Small-scale

0.714

High

966207

NC2B
Protein Dr1

4

2

Small-scale

0.694

High

638410

RBTN2
Rhombotin-2

3

2

High-throughput

0.683

High

899055

PSME3
Proteasome activator complex subunit 3

3

1

High-throughput

0.667

High

1160982

CTR9
RNA polymerase-associated protein CTR9 homolog

3

1

High-throughput

0.667

High

1070787

RBBP5
Retinoblastoma-binding protein 5

3

3

High-throughput

0.656

High

844261

FXR2
RNA-binding protein FXR2

2

1

High-throughput

0.640

High

1345365

MBIP1
MAP3K12-binding inhibitory protein 1

2

1

High-throughput

0.640

High

573088

PRS6A
26S proteasome regulatory subunit 6A

3

0

High-throughput

0.638

High

855954

ZN131
Zinc finger protein 131

3

0

High-throughput

0.638

High

1160850

RFWD3
E3 ubiquitin-protein ligase RFWD3

3

0

High-throughput

0.638

High

1301678

PRPK
EKC/KEOPS complex subunit TP53RK

3

0

High-throughput

0.638

High

1345380

CARD8
Caspase recruitment domain-containing protein 8

3

0

High-throughput

0.638

High

1345384

TPRKB
EKC/KEOPS complex subunit TPRKB

3

0

High-throughput

0.638

High

1232450

TXLNB
Beta-taxilin

4

1

High-throughput

0.637

High

616618

MYF6
Myogenic factor 6

2

1

High-throughput

0.628

High

1223269

EXOC8
Exocyst complex component 8

2

0

High-throughput

0.623

High

709076

MCM7
DNA replication licensing factor MCM7

2

0

High-throughput

0.618

High

854140

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

2

0

High-throughput

0.618

High

1326014

NDEL1
Nuclear distribution protein nudE-like 1

2

0

High-throughput

0.618

High

1345372

VPS28
Vacuolar protein sorting-associated protein 28 homolog

2

1

High-throughput

0.613

High

1025353

LIPA1
Liprin-alpha-1

2

0

High-throughput

0.613

High

63814

CC85C
Coiled-coil domain-containing protein 85C

3

1

High-throughput

0.609

High

274449

CRTAP
Cartilage-associated protein

3

1

High-throughput

0.609

High

1086975

KAT1
Kynurenine--oxoglutarate transaminase 1

2

0

High-throughput

0.602

High

1152395

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.602

High

1332090

IKZF5
Zinc finger protein Pegasus

2

0

High-throughput

0.602

High

1342727

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

2

0

High-throughput

0.602

High

1345371

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

2

3

High-throughput

0.584

High

1345383

E41L3
Band 4.1-like protein 3

2

1

High-throughput

0.584

High

1267446

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

1

High-throughput

0.576

High

770692

TXLNA
Alpha-taxilin

1

1

High-throughput

0.573

High

816285

LIMS1
LIM and senescent cell antigen-like-containing domain protein 1

1

1

High-throughput

0.560

High

348002

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

1104094

P3H1
Prolyl 3-hydroxylase 1

2

1

High-throughput

0.558

High

1328459

CAD19
Cadherin-19

2

1

High-throughput

0.558

High

169966

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.549

High

624516

CCNC
Cyclin-C

1

0

High-throughput

0.549

High

1216198

TF2LY
Homeobox protein TGIF2LY

1

0

High-throughput

0.549

High

1264489

ING5
Inhibitor of growth protein 5

1

0

High-throughput

0.549

High

1286010

MOAP1
Modulator of apoptosis 1

1

0

High-throughput

0.549

High

1345366

MS18A
Protein Mis18-alpha

1

0

High-throughput

0.549

High

595437

LMNB1
Lamin-B1

1

1

High-throughput

0.541

High

843928

FXR1
RNA-binding protein FXR1

1

1

High-throughput

0.541

High

639096

S100P
Protein S100-P

1

1

High-throughput

0.536

High

892062

ACTB
Actin, cytoplasmic 1

1

1

High-throughput

0.536

High

986854

PSME1
Proteasome activator complex subunit 1

1

1

High-throughput

0.536

High

1050815

FHL2
Four and a half LIM domains protein 2

1

1

High-throughput

0.536

High

1344242

DPOE4
DNA polymerase epsilon subunit 4

1

1

High-throughput

0.536

High

1293627

Q96HL7
EPB41L3 protein

2

1

High-throughput

0.533

High

1018213

M3K12
Mitogen-activated protein kinase kinase kinase 12

1

0

Small-scale

0.529

High

1017244

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.518

High

1047052

RPGF1
Rap guanine nucleotide exchange factor 1

1

0

High-throughput

0.518

High

1085520

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.518

High

1267559

TSC1
Hamartin

1

0

High-throughput

0.518

High

1298067

CEP63
Centrosomal protein of 63 kDa

1

0

High-throughput

0.518

High

1306785

MYD88
Myeloid differentiation primary response protein MyD88

1

0

High-throughput

0.518

High

1311904

CSN4
COP9 signalosome complex subunit 4

1

0

High-throughput

0.518

High

1316289

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

0

High-throughput

0.518

High

1342434

VTA1
Vacuolar protein sorting-associated protein VTA1 homolog

1

0

High-throughput

0.518

High

1345381

NINL
Ninein-like protein

1

0

High-throughput

0.518

High

932402

ACTC
Actin, alpha cardiac muscle 1

1

1

High-throughput

0.515

High

422302

NFL
Neurofilament light polypeptide

1

1

High-throughput

0.515

High

443842

VIME
Vimentin

1

1

High-throughput

0.515

High

535947

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.513

High

672319

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

0

High-throughput

0.513

High

871800

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.513

High

900080

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.513

High

933635

TBA4A
Tubulin alpha-4A chain

1

0

High-throughput

0.513

High

948848

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

0

High-throughput

0.513

High

1029332

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

1080907

HSPB2
Heat shock protein beta-2

1

0

High-throughput

0.513

High

1087433

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.513

High

1231862

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.513

High

1260602

BRK1
Protein BRICK1

1

0

High-throughput

0.513

High

1270232

THRSP
Thyroid hormone-inducible hepatic protein

1

0

High-throughput

0.513

High

1336542

BRMS1
Breast cancer metastasis-suppressor 1

1

0

High-throughput

0.513

High

1345379

RUVB2
RuvB-like 2

1

0

High-throughput

0.513

High

1345387

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

0

High-throughput

0.513

High

1079302

CC85B
Coiled-coil domain-containing protein 85B

1

1

High-throughput

0.494

High

1251471

LMO3
LIM domain only protein 3

1

2

High-throughput

0.494

High

1316048

DGC6L
Protein DGCR6L

1

2

High-throughput

0.494

High

1317520

TRI55
Tripartite motif-containing protein 55

1

1

High-throughput

0.494

High

218073

PEX1
Peroxisomal ATPase PEX1

1

0

High-throughput

0.493

High

281909

WFS1
Wolframin

1

0

High-throughput

0.493

High

592524

RAB5A
Ras-related protein Rab-5A

1

0

High-throughput

0.493

High

661459

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

68319

P20L1
PHD finger protein 20-like protein 1

1

2

High-throughput

0.479

High

165723

SET1A
Histone-lysine N-methyltransferase SETD1A

1

3

High-throughput

0.479

High

183165

KDM6A
Lysine-specific demethylase 6A

1

1

High-throughput

0.479

High

267798

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

1

3

High-throughput

0.479

High

546050

MYOD1
Myoblast determination protein 1

1

1

High-throughput

0.479

High

740609

PPARG
Peroxisome proliferator-activated receptor gamma

1

1

High-throughput

0.479

High

848299

HCFC1
Host cell factor 1

1

2

High-throughput

0.479

High

869545

ATN1
Atrophin-1

1

1

High-throughput

0.479

High

884253

KLF3
Krueppel-like factor 3

1

1

High-throughput

0.479

High

975332

KMT2A
Histone-lysine N-methyltransferase 2A

1

3

High-throughput

0.479

High

1083704

TAF9
Transcription initiation factor TFIID subunit 9

1

1

High-throughput

0.479

High

1159017

EDC4
Enhancer of mRNA-decapping protein 4

1

1

High-throughput

0.479

High

1198579

TAD2B
Transcriptional adapter 2-beta

1

3

High-throughput

0.479

High

1244520

NUP43
Nucleoporin Nup43

1

3

High-throughput

0.479

High

1281191

LHX4
LIM/homeobox protein Lhx4

1

1

High-throughput

0.479

High

1313845

PHF20
PHD finger protein 20

1

2

High-throughput

0.479

High

1335539

TAF9B
Transcription initiation factor TFIID subunit 9B

1

1

High-throughput

0.479

High

1345367

CXXC1
CXXC-type zinc finger protein 1

1

2

High-throughput

0.479

High

1345368

KANL3
KAT8 regulatory NSL complex subunit 3

1

1

High-throughput

0.479

High

1345370

RERE
Arginine-glutamic acid dipeptide repeats protein

1

3

High-throughput

0.479

High

1345373

RCOR1
REST corepressor 1

1

1

High-throughput

0.479

High

1345377

KMT2B
Histone-lysine N-methyltransferase 2B

1

3

High-throughput

0.479

High

1345378

SET1B
Histone-lysine N-methyltransferase SETD1B

1

3

High-throughput

0.479

High

1345386

KLF12
Krueppel-like factor 12

1

1

High-throughput

0.479

High

1345389

HCFC2
Host cell factor 2

1

2

High-throughput

0.479

High

1122110

Q548N1
Vacuolar protein sorting-associated protein 28 homolog

1

1

High-throughput

0.470

High

256350

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

0

High-throughput

0.458

High

266506

SUPT3
Transcription initiation protein SPT3 homolog

1

0

High-throughput

0.458

High

297937

ST65G
STAGA complex 65 subunit gamma

1

0

High-throughput

0.458

High

542076

ETS1
Protein C-ets-1

1

0

High-throughput

0.458

High

554523

GATA1
Erythroid transcription factor

1

0

High-throughput

0.458

High

632927

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.458

High

782671

HNF4A
Hepatocyte nuclear factor 4-alpha

1

0

High-throughput

0.458

High

813779

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.458

High

826362

CDK8
Cyclin-dependent kinase 8

1

0

High-throughput

0.458

High

900283

RL37A
Large ribosomal subunit protein eL43

1

0

High-throughput

0.458

High

918004

H4
Histone H4

1

0

High-throughput

0.458

High

963690

E2F1
Transcription factor E2F1

1

0

High-throughput

0.458

High

967468

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

1038749

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.458

High

1060375

NFIX
Nuclear factor 1 X-type

1

0

High-throughput

0.458

High

1188196

KANL1
KAT8 regulatory NSL complex subunit 1

1

0

High-throughput

0.458

High

1201461

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

0

High-throughput

0.458

High

1243315

SP20H
Transcription factor SPT20 homolog

1

0

High-throughput

0.458

High

1285369

PF21A
PHD finger protein 21A

1

0

High-throughput

0.458

High

1285675

TADA1
Transcriptional adapter 1

1

0

High-throughput

0.458

High

1290767

MCRS1
Microspherule protein 1

1

0

High-throughput

0.458

High

1326755

WWTR1
WW domain-containing transcription regulator protein 1

1

0

High-throughput

0.458

High

1333248

KAT8
Histone acetyltransferase KAT8

1

0

High-throughput

0.458

High

1334364

KANL2
KAT8 regulatory NSL complex subunit 2

1

0

High-throughput

0.458

High

1345369

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.458

High

1345374

ZN608
Zinc finger protein 608

1

0

High-throughput

0.458

High

1345375

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.458

High

1345385

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

1345391

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

0

High-throughput

0.458

High

1232034

Q8N381
Phosphoinositide-3-kinase, regulatory subunit 3

1

1

High-throughput

0.451

High

1048723

DGCR6
Protein DGCR6

1

2

High-throughput

0.439

High

1282051

TRI63
E3 ubiquitin-protein ligase TRIM63

1

1

High-throughput

0.439

High

174439

FANCG
Fanconi anemia group G protein

1

0

High-throughput

0.438

High

1293296

NTAQ1
Protein N-terminal glutamine amidohydrolase

1

0

High-throughput

0.438

High

1345382

WDR37
WD repeat-containing protein 37

1

3

High-throughput

0.437

High

1345392

X5DP20
DiGeorge syndrome critical region 6 isoform D

1

2

High-throughput

0.417

High

1296596

Q96KY9
CDH19 protein

1

1

High-throughput

0.407

High

1333861

PKHF2
Pleckstrin homology domain-containing family F member 2

3

0

High-throughput

0.358

High

1121498

KLH26
Kelch-like protein 26

3

0

High-throughput

0.347

High

1155883

PHLB3
Pleckstrin homology-like domain family B member 3

3

0

High-throughput

0.347

High

1161114

F199X
Protein FAM199X

3

0

High-throughput

0.347

High

1173407

STXB4
Syntaxin-binding protein 4

3

0

High-throughput

0.347

High

1294543

GMCL1
Germ cell-less protein-like 1

3

0

High-throughput

0.347

High

1037539

BFSP2
Phakinin

2

0

High-throughput

0.341

High

51113

CBAR1
CBY1-interacting BAR domain-containing protein 1

2

0

High-throughput

0.328

High

1238899

CBY2
Protein chibby homolog 2

2

0

High-throughput

0.328

High

339031

EGFR
Epidermal growth factor receptor

1

0

Small-scale

0.304

High

269489

STX11
Syntaxin-11

1

0

High-throughput

0.299

High

1057914

DIP2A
Disco-interacting protein 2 homolog A

1

0

High-throughput

0.299

High

1160006

KLC3
Kinesin light chain 3

1

0

High-throughput

0.299

High

1222448

DRC7
Dynein regulatory complex subunit 7

1

0

High-throughput

0.299

High

1231051

CRBG2
Beta/gamma crystallin domain-containing protein 2

1

0

High-throughput

0.279

Low

1302173

TCPQM
T-complex protein 1 subunit theta-like 2

1

0

High-throughput

0.279

Low

1329027

CAD23
Cadherin-23

1

0

High-throughput

0.279

Low

231733

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.268

Low

557500

PECA1
Platelet endothelial cell adhesion molecule

1

0

High-throughput

0.268

Low

609564

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low

1345390

Q9Y649
GW128

1

0

High-throughput

0.268

Low

1345388

CD2AP
CD2-associated protein

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024