HitPredict

Interactor 1: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Interactor 2: WDR3 (Q9UNX4)
WD repeat-containing protein 3
Gene: WDR3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	ANAPC4_WD40~WD40
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 342 Hs			1 943
+	Hs
		792935 LIS1_HUMAN (62-339): 9.49e-75: 238: 16.72		LIS1_HUMAN (187-484): 3.35e-46: 173: 11.78
+	Mm
		925836 LIS1_MOUSE (62-339): 6.17e-75: 238: 16.72		LIS1_MOUSE (187-484): 2.71e-46: 173: 11.78
+	Hs
		792949 LIS1_HUMAN (62-339): 9.49e-75: 238: 16.72		WDR5_HUMAN (663-860): 4.99e-35: 138: 10.89
+	Hs
		1240442 POC1B_HUMAN (163-340): 1.65e-45: 163: 21.79		POC1A_HUMAN (220-557): 9.69e-58: 205: 13.12
+	Hs
		903551 NLE1_HUMAN (114-333): 2.06e-53: 184: 18.05		WDR5_HUMAN (663-860): 4.99e-35: 138: 10.89
+	Hs
		725410 COPB2_HUMAN (54-331): 3.17e-47: 172: 18.38		WDR5_HUMAN (663-860): 4.99e-35: 138: 10.89
+	Hs
		793026 LIS1_HUMAN (62-339): 9.49e-75: 238: 16.72		KTNB1_HUMAN (409-625): 4.3e-09: 62.4: 22.27
+	Hs
		903418 FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29		WDR5_HUMAN (663-860): 4.99e-35: 138: 10.89
+	Ca
		483033 TUP1_CANAL (210-337): 1.63e-27: 114: 13.99		TUP1_CANAL (100-443): 3.29e-48: 181: 14.25
+	Hs
		254111 FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29		WDR1_HUMAN (603-905): 7.64e-26: 115: 10.00
+	Hs
		1281292 FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29		FBXW7_HUMAN (35-172): 1.4e-24: 112: 17.69
+	Sp
		999838 TUP11_SCHPO (210-336): 5.85e-28: 116: 13.24		TUP11_SCHPO (616-835): 6.07e-34: 140: 13.85
+	Hs
		1346954 NLE1_HUMAN (114-333): 2.06e-53: 184: 18.05		NLE1_HUMAN (748-843): 7.27e-09: 61.4: 4.12
+	Sp
		999842 TUP11_SCHPO (210-336): 5.85e-28: 116: 13.24		TUP12_SCHPO (624-835): 5.66e-29: 125: 12.22
+	Hs
		245633 TBL1X_HUMAN (162-342): 3.97e-28: 116: 15.46		TBL1R_HUMAN (3-138): 9.77e-27: 117: 17.93
+	Hs
		903077 WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79		WDR5_HUMAN (663-860): 4.99e-35: 138: 10.89
+	Sc
		630844 NLE1_YEAST (210-341): 6.38e-30: 121: 15.00		NLE1_YEAST (629-749): 1.33e-20: 98.5: 21.31
+	Hs
		1309163 TBL1Y_HUMAN (207-337): 6.68e-19: 89.3: 14.38		TBL1R_HUMAN (3-138): 9.77e-27: 117: 17.93