Protein: GID4
Glucose-induced degradation protein 4 homolog (Vacuolar import and degradation protein 24 homolog)

Gene: GID4
Organism: Homo sapiens
Interactions: 75
UniProt ID: Q8IVV7

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0005829 - cytosol
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0061630 - ubiquitin protein ligase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1309302

RANB9
Ran-binding protein 9

6

4

Small-scale

0.943

High

1250490

RBP10
Ran-binding protein 10

2

4

High-throughput

0.811

High

1309313

RMD5A
E3 ubiquitin-protein transferase RMND5A

6

5

Small-scale

0.733

High

1307877

ARMC8
Armadillo repeat-containing protein 8

6

2

Small-scale

0.729

High

1309312

WDR26
WD repeat-containing protein 26

3

1

Small-scale

0.656

High

1098575

GPS2
G protein pathway suppressor 2

3

0

High-throughput

0.638

High

1272699

MAEA
E3 ubiquitin-protein transferase MAEA

2

8

High-throughput

0.619

High

567911

PRG2
Bone marrow proteoglycan

3

1

High-throughput

0.609

High

1309317

GID8
Glucose-induced degradation protein 8 homolog

2

9

High-throughput

0.601

High

970740

UBE2H
Ubiquitin-conjugating enzyme E2 H

2

1

Small-scale

0.595

High

1309323

MKLN1
Muskelin

2

0

Small-scale

0.585

High

1309325

PRG3
Proteoglycan 3

2

1

High-throughput

0.574

High

480381

MMP7
Matrilysin

2

1

High-throughput

0.558

High

1122721

MPP2
MAGUK p55 subfamily member 2

2

1

High-throughput

0.558

High

568572

TNNT1
Troponin T, slow skeletal muscle

1

1

High-throughput

0.536

High

852110

TNNT3
Troponin T, fast skeletal muscle

1

1

High-throughput

0.536

High

1104608

IKZF1
DNA-binding protein Ikaros

1

1

High-throughput

0.536

High

1309292

KCTD6
BTB/POZ domain-containing protein KCTD6

1

0

High-throughput

0.513

High

1309306

CC106
Coiled-coil domain-containing protein 106

1

0

High-throughput

0.513

High

1309315

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.513

High

1309324

BAIP2
BAR/IMD domain-containing adapter protein 2

1

0

High-throughput

0.513

High

852313

MMP13
Collagenase 3

1

1

High-throughput

0.489

High

1309309

PDGFD
Platelet-derived growth factor D

1

1

High-throughput

0.489

High

1309326

RT02
Small ribosomal subunit protein uS2m

1

1

High-throughput

0.489

High

721723

GCH1
GTP cyclohydrolase 1

1

1

High-throughput

0.479

High

1309322

IKZF3
Zinc finger protein Aiolos

1

1

High-throughput

0.479

High

1100096

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1309293

NUP43
Nucleoporin Nup43

1

0

High-throughput

0.458

High

539206

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

1

High-throughput

0.437

High

95795

E5RI47
MAGUK p55 scaffold protein 2

1

1

High-throughput

0.407

High

561373

TDGF1
Protein Cripto

3

0

High-throughput

0.347

High

814920

GDNF
Glial cell line-derived neurotrophic factor

3

0

High-throughput

0.347

High

1194788

GRPL2
GLIPR1-like protein 2

3

0

High-throughput

0.347

High

1309308

RM04
Large ribosomal subunit protein uL4m

3

0

High-throughput

0.347

High

1309299

CC120
Coiled-coil domain-containing protein 120

3

0

High-throughput

0.345

High

230647

PRIC3
Prickle planar cell polarity protein 3

2

0

High-throughput

0.328

High

260695

CUTA
Protein CutA

2

0

High-throughput

0.328

High

278695

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

2

0

High-throughput

0.328

High

562741

BMP1
Bone morphogenetic protein 1

2

0

High-throughput

0.328

High

1198307

TIGD5
Tigger transposable element-derived protein 5

2

0

High-throughput

0.328

High

1309294

LIRB4
Leukocyte immunoglobulin-like receptor subfamily B member 4

2

0

High-throughput

0.328

High

1309295

NEUR4
Sialidase-4

2

0

High-throughput

0.328

High

1309296

PIGT
GPI-anchor transamidase component PIGT

2

0

High-throughput

0.328

High

1309300

JPH4
Junctophilin-4

2

0

High-throughput

0.328

High

1309329

INSL6
Insulin-like peptide INSL6

2

0

High-throughput

0.328

High

409589

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

2

0

High-throughput

0.318

High

652653

GNLY
Granulysin

2

0

High-throughput

0.313

High

1309316

EMIL3
EMILIN-3

2

0

High-throughput

0.313

High

1309320

TCAL9
Transcription elongation factor A protein-like 9

2

0

High-throughput

0.313

High

139072

LAD1
Ladinin-1

1

0

High-throughput

0.279

Low

169307

LECT2
Leukocyte cell-derived chemotaxin-2

1

0

High-throughput

0.279

Low

270261

MTG16
Protein CBFA2T3

1

0

High-throughput

0.279

Low

316674

LY6H
Lymphocyte antigen 6H

1

0

High-throughput

0.279

Low

377288

GLUC
Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide

1

0

High-throughput

0.279

Low

933197

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.279

Low

1179811

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1250846

CRDL2
Chordin-like protein 2

1

0

High-throughput

0.279

Low

1309298

RT24
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.279

Low

1309304

GDF15
Growth/differentiation factor 15

1

0

High-throughput

0.279

Low

1309305

DDX50
ATP-dependent RNA helicase DDX50

1

0

High-throughput

0.279

Low

1309310

WN10A
Protein Wnt-10a

1

0

High-throughput

0.279

Low

1309311

RM18
Large ribosomal subunit protein uL18m

1

0

High-throughput

0.279

Low

1309314

SPON1
Spondin-1

1

0

High-throughput

0.279

Low

1309319

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

0

High-throughput

0.279

Low

1309321

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.279

Low

1309327

COQ4
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial

1

0

High-throughput

0.279

Low

1309328

RT23
Small ribosomal subunit protein mS23

1

0

High-throughput

0.279

Low

1309297

ZMY19
Zinc finger MYND domain-containing protein 19

1

0

Small-scale

0.261

Low

248321

HBP1
HMG box-containing protein 1

1

0

High-throughput

0.249

Low

615187

PACA
Pituitary adenylate cyclase-activating polypeptide

1

0

High-throughput

0.249

Low

1309318

RM39
Large ribosomal subunit protein mL39

1

0

High-throughput

0.249

Low

1309291

SYT2
Synaptotagmin-2

1

0

High-throughput

0.232

Low

1309301

PEO1
Twinkle mtDNA helicase

1

0

High-throughput

0.232

Low

1309303

HPLN3
Hyaluronan and proteoglycan link protein 3

1

0

High-throughput

0.232

Low

1309307

C1QT1
Complement C1q tumor necrosis factor-related protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025