Protein: GID4
GID complex substrate-recognition subunit 4 (Glucose-induced degradation protein 4) (Vacuolar import and degradation protein 24)

Gene: GID4, VID24
Organism: Saccharomyces cerevisiae S288C
Interactions: 165
UniProt ID: P38263

Gene Ontology (top 5):
GO:0005773 - vacuole
GO:0005829 - cytosol
GO:0006623 - protein targeting to vacuole
GO:0007039 - protein catabolic process in the vacuole
GO:0030659 - cytoplasmic vesicle membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

796883

VID30
GID complex subunit 1

8

3

Small-scale

0.965

High

796871

VID28
GID complex subunit 5

6

2

Small-scale

0.725

High

796868

GID8
GID complex subunit 8

5

1

Small-scale

0.706

High

796869

FYV10
GID complex subunit 9

4

4

Small-scale

0.683

High

644622

MDHC
Malate dehydrogenase, cytoplasmic

3

1

Small-scale

0.662

High

677029

GID7
GID complex subunit 7

3

1

Small-scale

0.656

High

479680

F16P
Fructose-1,6-bisphosphatase

3

1

Small-scale

0.650

High

671413

RNA14
mRNA 3'-end-processing protein RNA14

2

0

High-throughput

0.595

High

626710

HSP60
Heat shock protein 60, mitochondrial

2

0

High-throughput

0.585

High

796872

MKT1
Post-transcriptional regulator MKT1

2

0

High-throughput

0.585

High

796897

RL13A
Large ribosomal subunit protein eL13A

2

0

High-throughput

0.585

High

796896

RMD5
E3 ubiquitin-protein ligase RMD5

2

3

Small-scale

0.584

High

523750

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.571

High

526527

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.571

High

544649

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.571

High

796866

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

High-throughput

0.571

High

796876

RSSA2
Small ribosomal subunit protein uS2B

2

1

High-throughput

0.571

High

514273

RL12B
Large ribosomal subunit protein uL11B

2

0

High-throughput

0.559

High

394495

EF1A
Elongation factor 1-alpha

2

0

High-throughput

0.547

High

453562

PYR1
Multifunctional protein URA2

2

0

High-throughput

0.547

High

734081

EF2
Elongation factor 2

2

0

High-throughput

0.547

High

592202

VATB
V-type proton ATPase subunit B

2

2

High-throughput

0.521

High

701593

UBC8
Ubiquitin-conjugating enzyme E2-24 kDa

1

1

Small-scale

0.501

High

470515

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

High-throughput

0.489

High

644917

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

1

High-throughput

0.489

High

534182

PCKA
Phosphoenolpyruvate carboxykinase

1

0

Small-scale

0.480

High

359004

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.479

High

359207

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

1

High-throughput

0.479

High

367011

ATPB
ATP synthase subunit beta, mitochondrial

1

2

High-throughput

0.479

High

409723

RL24A
Large ribosomal subunit protein eL24A

1

1

High-throughput

0.479

High

753331

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

433190

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.479

High

439320

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.479

High

452893

ATPA
ATP synthase subunit alpha, mitochondrial

1

2

High-throughput

0.479

High

579286

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

596924

PDC5
Pyruvate decarboxylase isozyme 2

1

1

High-throughput

0.479

High

601029

RL8A
Large ribosomal subunit protein eL8A

1

1

High-throughput

0.479

High

645727

HSP74
Heat shock protein SSA4

1

2

High-throughput

0.479

High

655442

RS3A2
Small ribosomal subunit protein eS1B

1

1

High-throughput

0.479

High

663669

RL24B
Large ribosomal subunit protein eL24B

1

1

High-throughput

0.479

High

670622

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

675951

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.479

High

689016

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.479

High

689201

RL16B
Large ribosomal subunit protein uL13B

1

1

High-throughput

0.479

High

689416

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.479

High

712551

RL8B
Large ribosomal subunit protein eL8B

1

1

High-throughput

0.479

High

741457

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.479

High

796858

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.479

High

796877

RL17B
Large ribosomal subunit protein uL22B

1

1

High-throughput

0.479

High

796879

RS7B
Small ribosomal subunit protein eS7B

1

1

High-throughput

0.479

High

701482

ACEA
Isocitrate lyase

1

0

Small-scale

0.460

High

365606

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.458

High

367952

ENO2
Enolase 2

1

0

High-throughput

0.458

High

368437

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

368650

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.458

High

383297

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.458

High

383668

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

403490

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.458

High

410089

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

420924

PMA1
Plasma membrane ATPase 1

1

0

High-throughput

0.458

High

432831

RL9A
Large ribosomal subunit protein uL6A

1

0

High-throughput

0.458

High

434006

RL33A
Large ribosomal subunit protein eL33A

1

0

High-throughput

0.458

High

434154

RL36A
Large ribosomal subunit protein eL36A

1

0

High-throughput

0.458

High

434359

RL15A
Large ribosomal subunit protein eL15A

1

0

High-throughput

0.458

High

434552

RL22A
Large ribosomal subunit protein eL22A

1

0

High-throughput

0.458

High

435046

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

435554

RS9B
Small ribosomal subunit protein uS4B

1

0

High-throughput

0.458

High

435924

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

436391

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

450574

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.458

High

455026

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

503380

RL11A
Large ribosomal subunit protein uL5A

1

0

High-throughput

0.458

High

503911

RL27B
Large ribosomal subunit protein eL27B

1

0

High-throughput

0.458

High

504524

RL31B
Large ribosomal subunit protein eL31B

1

0

High-throughput

0.458

High

511179

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.458

High

511783

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.458

High

512064

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.458

High

512405

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

512971

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

513354

RL23B
Large ribosomal subunit protein uL14B

1

0

High-throughput

0.458

High

513490

RL1A
Large ribosomal subunit protein uL1A

1

0

High-throughput

0.458

High

513853

RS11B
Small ribosomal subunit protein uS17B

1

0

High-throughput

0.458

High

513985

RL18B
Large ribosomal subunit protein eL18B

1

0

High-throughput

0.458

High

514130

RS16B
Small ribosomal subunit protein uS9B

1

0

High-throughput

0.458

High

514607

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

515085

RL19B
Large ribosomal subunit protein eL19

1

0

High-throughput

0.458

High

515245

RL35A
Large ribosomal subunit protein uL29A

1

0

High-throughput

0.458

High

531311

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.458

High

555064

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

569768

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.458

High

569987

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

572566

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

673094

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.458

High

674584

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

679609

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

684701

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.458

High

688871

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.458

High

760577

TSA1
Peroxiredoxin TSA1

1

0

High-throughput

0.458

High

781174

RL14A
Large ribosomal subunit protein eL14A

1

0

High-throughput

0.458

High

792009

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

792507

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.458

High

796856

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

796857

RS27B
Small ribosomal subunit protein eS27B

1

0

High-throughput

0.458

High

796864

RS14B
Small ribosomal subunit protein uS11B

1

0

High-throughput

0.458

High

796865

RS26B
Small ribosomal subunit protein eS26B

1

0

High-throughput

0.458

High

796873

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.458

High

796880

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

796881

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.458

High

796885

PBP1
PAB1-binding protein 1

1

0

High-throughput

0.458

High

796886

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

0

High-throughput

0.458

High

796888

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

796889

RL6A
Large ribosomal subunit protein eL6A

1

0

High-throughput

0.458

High

796890

RL21A
Large ribosomal subunit protein eL21A

1

0

High-throughput

0.458

High

796891

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

796894

RL7B
Large ribosomal subunit protein uL30B

1

0

High-throughput

0.458

High

796898

RS21B
Small ribosomal subunit protein eS21B

1

0

High-throughput

0.458

High

796899

RS22B
Small ribosomal subunit protein uS8B

1

0

High-throughput

0.458

High

392636

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

598851

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

1

High-throughput

0.437

High

599004

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

1

High-throughput

0.437

High

603459

VATA
V-type proton ATPase catalytic subunit A

1

3

High-throughput

0.437

High

737453

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

1

High-throughput

0.437

High

740899

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

1

High-throughput

0.437

High

796863

XDJ1
DnaJ protein homolog XDJ1

1

1

High-throughput

0.407

High

796893

GID12
GID complex associated protein 12

3

0

Small-scale

0.334

High

427248

RLA0
Large ribosomal subunit protein uL10

2

0

High-throughput

0.318

High

796870

COPE
Coatomer subunit epsilon

2

0

Small-scale

0.305

High

365025

KPYK1
Pyruvate kinase 1

2

0

High-throughput

0.298

High

386685

TBB
Tubulin beta chain

2

0

High-throughput

0.298

High

796884

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.282

High

721888

XPO1
Exportin-1

1

0

High-throughput

0.279

Low

796895

HSP42
Heat shock protein 42

1

0

High-throughput

0.279

Low

358197

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.249

Low

417085

VDAC1
Non-selective voltage-gated ion channel 1

1

0

High-throughput

0.249

Low

419415

H2A1
Histone H2A.1

1

0

High-throughput

0.249

Low

427691

RLA2
Large ribosomal subunit protein P2A

1

0

High-throughput

0.249

Low

510433

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.249

Low

514997

YE11A
Transposon Ty1-ER1 Gag polyprotein

1

0

High-throughput

0.249

Low

518274

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.249

Low

528815

RLA3
Large ribosomal subunit protein P1B

1

0

High-throughput

0.249

Low

575440

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.249

Low

575933

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.249

Low

585616

STI1
Heat shock protein STI1

1

0

High-throughput

0.249

Low

597444

EF3A
Elongation factor 3A

1

0

High-throughput

0.249

Low

600639

FCY2
Purine-cytosine permease FCY2

1

0

High-throughput

0.249

Low

610138

PDI
Protein disulfide-isomerase

1

0

High-throughput

0.249

Low

673331

TRX3
Thioredoxin-3, mitochondrial

1

0

High-throughput

0.249

Low

701515

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

0

High-throughput

0.249

Low

706925

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

720859

ITR2
Myo-inositol transporter 2

1

0

High-throughput

0.249

Low

724330

DHOM
Homoserine dehydrogenase

1

0

High-throughput

0.249

Low

740652

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.249

Low

794074

MCM7
DNA replication licensing factor MCM7

1

0

High-throughput

0.249

Low

796859

LSM12
Protein LSM12

1

0

High-throughput

0.249

Low

796860

SMC2
Structural maintenance of chromosomes protein 2

1

0

High-throughput

0.249

Low

796861

STM1
Suppressor protein STM1

1

0

High-throughput

0.249

Low

796862

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.249

Low

796867

VID27
Vacuolar import and degradation protein 27

1

0

Small-scale

0.249

Low

796874

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.249

Low

796875

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.249

Low

796878

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.249

Low

796882

EXG2
Glucan 1,3-beta-glucosidase 2

1

0

High-throughput

0.249

Low

796887

ACT
Actin

1

0

High-throughput

0.249

Low

796892

EAF1
Chromatin modification-related protein EAF1

1

0

Small-scale

0.249

Low

382058

H4
Histone H4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025