Interactor 1: SLD5 (Q9BRT9)
DNA replication complex GINS protein SLD5 (GINS complex subunit 4) [Cleaved into: DNA replication complex GINS protein SLD5, N-terminally processed]
Gene: GINS4

Interactor 2: PSF2 (Q9Y248)
DNA replication complex GINS protein PSF2 (GINS complex subunit 2)
Gene: GINS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 34195792, 21705323, 25416956, 16189514, 32296183, 33961781, 31515488, unassigned1304
Identification Methods affinity chromatography technology, pull down, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Sld5~Sld5, SLD5_C~Sld5
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0000811 - GINS complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006268 - DNA unwinding involved in DNA replication
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 223
Hs

1 185
+ Mm
+ Dm
+ Ce
+ Sp
+ Sc
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024