HitPredict

Interactor 1: MTA3 (Q9BTC8)
Metastasis-associated protein MTA3
Gene: MTA3

Interactor 2: RCOR3 (Q9P2K3)
REST corepressor 3
Gene: RCOR3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	21258344
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Myb_DNA-binding~Myb_DNA-binding
Common GO terms	GO:0003714 - transcription corepressor activity GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 594 Hs			1 495
+	Hs
		1312042 MTA3_HUMAN (1-594): 0: 724: 100.00		RCOR1_HUMAN (1-384): 4.93e-99: 308: 62.69
+	Hs
		296120 MTA3_HUMAN (1-594): 0: 724: 100.00		MTA2_HUMAN (1-478): 7.19e-92: 295: 15.71
+	Hs
		1031940 MTA3_HUMAN (1-594): 0: 724: 100.00		MTA1_HUMAN (1-433): 2.17e-85: 279: 15.62
+	Mm
		1225272 MTA1_MOUSE (1-586): 0: 625: 68.81		MTA2_MOUSE (1-478): 1.74e-92: 297: 15.53
+	Hs
		296011 MTA1_HUMAN (1-586): 0: 627: 69.14		MTA2_HUMAN (1-478): 7.19e-92: 295: 15.71
+	Mm
		1351670 MTA2_MOUSE (1-584): 0: 613: 64.57		MTA2_MOUSE (1-478): 1.74e-92: 297: 15.53
+	Hs
		295897 MTA2_HUMAN (1-584): 0: 611: 64.40		MTA2_HUMAN (1-478): 7.19e-92: 295: 15.71
+	Hs
		1350408 RCOR3_HUMAN (150-571): 3.76e-83: 270: 19.03		RCOR1_HUMAN (1-384): 4.93e-99: 308: 62.69
+	Hs
		1356481 RCOR1_HUMAN (148-567): 3.74e-78: 257: 16.63		RCOR1_HUMAN (1-384): 4.93e-99: 308: 62.69
+	Hs
		261618 NCOR2_HUMAN (53-566): 2.01e-95: 322: 14.10		NCOR1_HUMAN (35-484): 1.63e-51: 191: 17.04
+	Hs
		1162165 MDEAS_HUMAN (142-457): 8.31e-49: 185: 14.82		TREF1_HUMAN (1-314): 6.01e-45: 171: 20.48