Interactor 1: BIN1 (O00499)
Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Box-dependent myc-interacting protein 1) (Bridging integrator 1)
Gene: BIN1

Interactor 2: AMPH (P49418)
Amphiphysin
Gene: AMPH

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.948

The method score is based on:

Property Details
Experiments 28514442, 9348539, 33961781, 9315708, 35271311, unassigned1973
Identification Methods affinity chromatography technology, pull down, two hybrid fragment pooling approach, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains BAR~BAR
Common GO terms GO:0005543 - phospholipid binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006897 - endocytosis
GO:0008021 - synaptic vesicle
and 2 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 593
Hs

1 695
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Ca
+ Sc
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024