HitPredict

Interactor 1: PSMD7 (P26270)
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Proteasome subunit p39B) (Proteasome subunit p40) (Protein Mov34)
Gene: Rpn8

Interactor 2: PSDE (Q9V3H2)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory complex subunit p37B) (26S proteasome regulatory subunit rpn11) (Yippee-interacting protein 5)
Gene: Rpn11

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.874

The method score is based on:

Property Details
Experiments 14605208, 22036573, 19079254, 38944040
Identification Methods two hybrid, affinity chromatography technology, two hybrid array, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~JAB, JAB~MitMem_reg
Common GO terms GO:0000502 - proteasome complex
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005838 - proteasome regulatory particle
GO:0008541 - proteasome regulatory particle, lid subcomplex
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 338
Dm

1 308
+ Hs
+ Sp
+ Ce
+ Sc
+ Mm
+ Dm
+ Hs
+ Hs
+ At
+ At
+ Hs
+ At
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Sc

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Last updated: 11Aug2025