HitPredict

Interactor 1: PSDE (O00487)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)
Gene: PSMD14

Interactor 2: PSMD7 (P51665)
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)
Gene: PSMD7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 25416956, 26186194, 28514442, 32296183, 33961781, 39358380, 31839598, 19615732, 26496610, 27428775, 28821611, 28292943, 35530310, 35235311, 37071682, 26414014, 40437099, 20656689, 17323924, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, cross-linking study, pull down, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~JAB, JAB~MitMem_reg
Common GO terms GO:0000502 - proteasome complex
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 310
Hs

1 324
+ Dm
+ Sp
+ Ce
+ Sc
+ Hs
+ Mm
+ Hs
+ Dm
+ At
+ At
+ At
+ At
+ At
+ Zm
+ Zm
+ An
+ Hs
+ Ce
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 11Aug2025