HitPredict

Interactor 1: TRAF4 (Q9BUZ4)
TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83)
Gene: TRAF4

Interactor 2: TRAF4 (Q9BUZ4)
TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83)
Gene: TRAF4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.742

The method score is based on:

Property Details
Experiments 25416956, 24311986, 27107012, 32296183, 9718306, unassigned1304
Identification Methods two hybrid, pull down, affinity chromatography technology, two hybrid array, barcode fusion genetics two hybrid, validated two hybrid, x-ray crystallography, mass spectrometry studies of complexes, molecular sieving, dynamic light scattering and 1 others

more...
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001650 - fibrillar center
GO:0005164 - tumor necrosis factor receptor binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 22 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 470
Hs

1 470
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024