HitPredict

Interactor 1: SHAN3 (Q9BYB0)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2)
Gene: SHANK3

Interactor 2: ABI2 (Q9NYB9)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 21653829
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~SH3_1, SH3_1~SH3_2
Common GO terms GO:0005829 - cytosol
GO:0017124 - SH3 domain binding
GO:0043197 - dendritic spine
GO:0061001 - regulation of dendritic spine morphogenesis
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1731
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024