HitPredict - High confidence protein-protein interactions

Method score	Annotation score	Interaction score
0.98	0.90	0.940

Property	Details
Experiments	32132184, 888800000006, 888800000035, 888800000125, 34927585, 34709727, 888800000479, 888800000611, 888800000619, 888800000620, 35790190, 36640338, 36584595, 888800000995, 36068861, 36317551, 37499664, 37000485, 33481336, 888800001009 and 5 others more... 888800001019, 34012108, 38245532, 16166518, 32678978
Identification Methods	x-ray crystallography, pull down, affinity chromatography technology, proximity labelling technology, protein complementation assay, biochemical, mass spectrometry studies of complexes
Interaction Type	association, direct interaction, physical association

Property	Details
Interacting Pfam domains	Collectrin~Collectrin, Collectrin~Peptidase_M2, Peptidase_M2~Peptidase_M2
Common GO terms	GO:0001618 - virus receptor activity GO:0001817 - regulation of cytokine production GO:0002003 - angiotensin maturation GO:0003051 - angiotensin-mediated drinking behavior GO:0003081 - regulation of systemic arterial blood pressure by renin-angiotensin and 40 others more... GO:0004175 - endopeptidase activity GO:0004180 - carboxypeptidase activity GO:0004181 - metallocarboxypeptidase activity GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0005788 - endoplasmic reticulum lumen GO:0005886 - plasma membrane GO:0005929 - cilium GO:0008237 - metallopeptidase activity GO:0008241 - peptidyl-dipeptidase activity GO:0008270 - zinc ion binding GO:0009986 - cell surface GO:0015827 - tryptophan transport GO:0016020 - membrane GO:0016324 - apical plasma membrane GO:0019058 - viral life cycle GO:0019065 - receptor-mediated endocytosis of virus by host cell GO:0019229 - regulation of vasoconstriction GO:0022898 - regulation of transmembrane transporter activity GO:0030666 - endocytic vesicle membrane GO:0031526 - brush border membrane GO:0042127 - regulation of cell population proliferation GO:0045121 - membrane raft GO:0046718 - symbiont entry into host cell GO:0046813 - receptor-mediated virion attachment to host cell GO:0048662 - negative regulation of smooth muscle cell proliferation GO:0050727 - regulation of inflammatory response GO:0051957 - positive regulation of amino acid transport GO:0060135 - maternal process involved in female pregnancy GO:0060452 - positive regulation of cardiac muscle contraction GO:0061025 - membrane fusion GO:0070062 - extracellular exosome GO:0070373 - negative regulation of ERK1 and ERK2 cascade GO:0097746 - blood vessel diameter maintenance GO:0098670 - entry receptor-mediated virion attachment to host cell GO:1903598 - positive regulation of gap junction assembly GO:1903779 - regulation of cardiac conduction GO:1905737 - positive regulation of L-proline import across plasma membrane GO:2000272 - negative regulation of signaling receptor activity GO:2000379 - positive regulation of reactive oxygen species metabolic process
Homologous interactions	0