HitPredict

Interactor 1: ABI3 (Q9P2A4)
ABI gene family member 3 (New molecule including SH3) (Nesh)
Gene: ABI3

Interactor 2: NCKP1 (Q9Y2A7)
Nck-associated protein 1 (NAP 1) (Membrane-associated protein HEM-2) (p125Nap1)
Gene: NCKAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Abi_HHR~Nckap1
Common GO terms	GO:0030027 - lamellipodium GO:0031209 - SCAR complex
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 366 Hs			1 1128
+	Mm
		704273 ABI2_MOUSE (1-363): 1.19e-86: 270: 34.40		NCKP1_MOUSE (1-1128): 0: 1691: 99.38
+	Mm
		704295 ABI1_MOUSE (1-314): 3.09e-64: 213: 34.35		NCKP1_MOUSE (1-1128): 0: 1691: 99.38
+	Hs
		1452530 ABI2_HUMAN (109-363): 1.97e-25: 108: 23.18		NCKP1_HUMAN (1-1128): 0: 1697: 100.00
+	Hs
		1316726 ABI1_HUMAN (124-363): 6.4e-21: 95.9: 24.49		NCKP1_HUMAN (1-1128): 0: 1697: 100.00
+	Hs
		988046 GRB2_HUMAN (312-363): 4.05e-14: 72.7: 28.30		NCKP1_HUMAN (1-1128): 0: 1697: 100.00
+	Mm
		1298230 ABI1_MOUSE (1-314): 3.09e-64: 213: 34.35		NCKPL_MOUSE (4-1121): 0: 1526: 58.88
+	Hs
		936244 ABI2_HUMAN (109-363): 1.97e-25: 108: 23.18		NCKPL_HUMAN (4-1121): 0: 1560: 59.23
+	Dm
		936258 Q9Y0S9_DROME (260-364): 6.86e-21: 95.5: 38.32		HEM_DROME (1-1122): 0: 1545: 59.57
+	Mm
		1297471 ABI1_MOUSE (1-314): 3.09e-64: 213: 34.35		Q8BVQ3_MOUSE (811-1121): 9.79e-137: 418: 60.77