Interactor 1: TRAF6 (P70196)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Interactor 2: IRAK2 (Q8CFA1)
Interleukin-1 receptor-associated kinase-like 2 (IRAK-2) (mu-IRAK-2)
Gene: IRAK2

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 19224918
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0007249 - canonical NF-kappaB signal transduction
GO:0031663 - lipopolysaccharide-mediated signaling pathway
GO:0034142 - toll-like receptor 4 signaling pathway
and 2 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 530
Mm

1 622
+ Hs
+ Hs
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+ Mm
+ Mm
+ Hs
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+ Dm
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+ Mm

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Last updated: 15 Jul 2024