Interactor 1: PREP (Q8K411)
Presequence protease, mitochondrial (EC 3.4.24.-) (Pitrilysin metalloproteinase 1)
Gene: Pitrm1

Interactor 2: PREP (Q8K411)
Presequence protease, mitochondrial (EC 3.4.24.-) (Pitrilysin metalloproteinase 1)
Gene: Pitrm1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 29199018, 29222160, 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains M16C_assoc~M16C_assoc, M16C_assoc~Peptidase_M16, M16C_assoc~Peptidase_M16_C, M16C_assoc~PreP_C, Peptidase_M16~Peptidase_M16, Peptidase_M16~Peptidase_M16_C, Peptidase_M16~PreP_C, Peptidase_M16_C~Peptidase_M16_C
Common GO terms GO:0004222 - metalloendopeptidase activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006508 - proteolysis
GO:0008270 - zinc ion binding
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1036
Mm

1 1036
+ Hs
+ Sc
+ Hs
+ Zm
+ Zm
+ Dm
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025