HitPredict

Interactor 1: DPY30 (Q9C005)
Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L)
Gene: DPY30

Interactor 2: SET1B (Q9UPS6)
Histone-lysine N-methyltransferase SETD1B (EC 2.1.1.364) (Lysine N-methyltransferase 2G) (SET domain-containing protein 1B) (hSET1B)
Gene: SETD1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 24981860
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0035097 - histone methyltransferase complex GO:0048188 - Set1C/COMPASS complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 99 Hs			1 1966
+	Hs
		1318622 DPY30_HUMAN (1-99): 2.56e-50: 155: 100.00		KMT2B_HUMAN (1069-1966): 4.68e-71: 268: 21.69
+	Hs
		975318 DPY30_HUMAN (1-99): 2.56e-50: 155: 100.00		KMT2A_HUMAN (1173-1966): 2.68e-66: 252: 21.73
+	Hs
		1243840 DPY30_HUMAN (1-99): 2.56e-50: 155: 100.00		KMT2C_HUMAN (1759-1966): 1.32e-58: 227: 37.04
+	Hs
		165713 DPY30_HUMAN (1-99): 2.56e-50: 155: 100.00		SET1A_HUMAN (409-1966): 1e-54: 214: 22.13
+	Sp
		252202 SDC1_SCHPO (48-89): 9.88e-13: 60.5: 47.62		SET1_SCHPO (1461-1966): 2.02e-73: 267: 24.62
+	Dm
		1129081 DPY30_DROME (42-99): 1.39e-24: 91.7: 51.72		SET1_DROME (30-197): 5.94e-53: 208: 38.60
+	Hs
		152687 DPY30_HUMAN (1-99): 2.56e-50: 155: 100.00		KMT2D_HUMAN (1826-1966): 3.07e-17: 91.3: 46.85