HitPredict

Interactor 1: TMTC2 (Q8N394)
Protein O-mannosyl-transferase TMTC2 (EC 2.4.1.109) (Transmembrane O-mannosyltransferase targeting cadherins 2) (Transmembrane and tetratricopeptide repeat-containing 2)
Gene: TMTC2

Interactor 2: PCDBB (Q9Y5F2)
Protocadherin beta-11 (PCDH-beta-11)
Gene: PCDHB11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 836 Hs			1 797
+	Hs
		1324948 TMTC2_HUMAN (1-836): 0: 667: 100.00		PCDB3_HUMAN (1-796): 0: 1013: 75.25
+	Hs
		1324947 TMTC2_HUMAN (1-836): 0: 667: 100.00		PCDB7_HUMAN (1-795): 0: 984: 72.96
+	Hs
		1324950 TMTC2_HUMAN (1-836): 0: 667: 100.00		PCDGD_HUMAN (1-792): 0: 903: 40.54
+	Hs
		1098510 DNJC3_HUMAN (699-832): 2.55e-14: 78.3: 18.98		PCDBB_HUMAN (1-797): 0: 1027: 100.00
+	Hs
		1257566 TMTC3_HUMAN (643-835): 4.46e-26: 117: 20.67		PCDB7_HUMAN (1-795): 0: 984: 72.96
+	Hs
		1098509 DNJC3_HUMAN (699-832): 2.55e-14: 78.3: 18.98		PCDB3_HUMAN (1-796): 0: 1013: 75.25
+	Hs
		1098508 DNJC3_HUMAN (699-832): 2.55e-14: 78.3: 18.98		PCDB7_HUMAN (1-795): 0: 984: 72.96
+	Hs
		1212736 TMTC4_HUMAN (645-834): 2.88e-26: 117: 22.63		PCDG5_HUMAN (1-792): 0: 922: 43.84
+	Hs
		1383800 TTC28_HUMAN (441-834): 7.26e-26: 117: 12.38		PCDGD_HUMAN (1-792): 0: 903: 40.54
+	Hs
		1257567 TMTC3_HUMAN (643-835): 4.46e-26: 117: 20.67		PCDB1_HUMAN (1-796): 0: 891: 49.63
+	Hs
		1212735 TMTC4_HUMAN (645-834): 2.88e-26: 117: 22.63		PCDGM_HUMAN (33-770): 0: 547: 41.22