HitPredict

Interactor 1: RPA49 (Q9GZS1)
DNA-directed RNA polymerase I subunit RPA49 (RNA polymerase I subunit A49) (DNA-directed RNA polymerase I subunit E) (RNA polymerase I-associated factor 1) (RNA polymerase I-associated factor 53)
Gene: POLR1E

Interactor 2: Q9H6S8 (Q9H6S8)
DNA-directed RNA polymerase I subunit RPA2 (EC 2.7.7.6)
Gene: Q9H6S8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RNA_pol_I_A49~RNA_pol_Rpb2_6, RNA_pol_I_A49~RNA_pol_Rpb2_7
Common GO terms	GO:0003677 - DNA binding GO:0005736 - RNA polymerase I complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 419 Hs			1 459
+	Hs
		1326416 RPA49_HUMAN (1-419): 0: 544: 100.00		RPA2_HUMAN (1-444): 0: 730: 97.30
+	Mm
		936933 RPA49_MOUSE (4-418): 0: 514: 69.55		RPA2_MOUSE (1-444): 0: 717: 91.89
+	Hs
		676994 RPA49_HUMAN (1-419): 0: 544: 100.00		RPB2_HUMAN (5-433): 0: 653: 39.78
+	Hs
		1326435 RPA49_HUMAN (1-419): 0: 544: 100.00		RPC2_HUMAN (2-435): 0: 638: 39.29
+	Sc
		604601 RPA49_YEAST (16-417): 4.24e-109: 329: 19.66		RPA2_YEAST (1-438): 0: 643: 54.30