HitPredict

Interactor 1: SDCB1 (O00560)
Syntenin-1 (Melanoma differentiation-associated protein 9) (MDA-9) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18) (Scaffold protein Pbp1) (Syndecan-binding protein 1)
Gene: SDCBP

Interactor 2: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005634 - nucleus GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030335 - positive regulation of cell migration and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 298 Hs			1 193
+	Hs
		132808 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Hs
		132816 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22
+	Hs
		132805 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30
+	Hs
		132735 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12
+	Hs
		132812 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82
+	Hs
		132804 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54
+	Hs
		900616 PREX2_HUMAN (108-256): 2.7e-39: 148: 20.40		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Hs
		925382 PREX2_HUMAN (108-256): 2.7e-39: 148: 20.40		RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22
+	Hs
		951099 PREX2_HUMAN (108-256): 2.7e-39: 148: 20.40		RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92
+	Hs
		894155 PREX2_HUMAN (108-256): 2.7e-39: 148: 20.40		CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30
+	Hs
		900762 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Mm
		925797 DLG4_MOUSE (193-286): 2.27e-16: 81.4: 24.75		RAC1_MOUSE (1-193): 7.23e-81: 240: 57.22
+	Hs
		436297 SCRIB_HUMAN (161-276): 6.09e-16: 80.2: 18.61		RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00
+	Hs
		951207 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92
+	Hs
		915880 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82
+	Hs
		893999 SCRIB_HUMAN (161-276): 6.09e-16: 80.2: 18.61		CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30
+	Hs
		545370 SCRIB_HUMAN (161-276): 6.09e-16: 80.2: 18.61		RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12
+	Mm
		1111996 DLG4_MOUSE (193-286): 2.27e-16: 81.4: 24.75		Q3TLP8_MOUSE (1-193): 3.07e-76: 229: 51.64
+	Hs
		892525 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54
+	Hs
		892367 SCRIB_HUMAN (161-276): 6.09e-16: 80.2: 18.61		RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54