Protein: PER
Period circadian protein (Protein clock-6) (CLK-6)

Gene: PER
Organism: Drosophila melanogaster
Interactions: 31
UniProt ID: P07663

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0001222 - transcription corepressor binding
GO:0003712 - transcription coregulator activity
GO:0003714 - transcription corepressor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

263802

CLOCK
Circadian locomoter output cycles protein kaput

11

20

Small-scale

0.968

High

458791

PER
Period circadian protein

3

19

Small-scale

0.847

High

458799

TIM
Protein timeless

19

4

Small-scale

0.763

High

303768

DCO
Discs overgrown protein kinase

14

20

Small-scale

0.760

High

304907

CRY1
Cryptochrome-1

9

20

Small-scale

0.747

High

194881

ARNT
Aryl hydrocarbon receptor nuclear translocator homolog

1

20

Small-scale

0.647

High

263791

CYCL
Protein cycle

1

20

Small-scale

0.618

High

458792

CSK2A
Casein kinase II subunit alpha

2

6

Small-scale

0.611

High

458807

Q9VDE3
LD08669p

2

11

Small-scale

0.584

High

458802

DICH
SOX domain-containing protein dichaete

2

17

Small-scale

0.545

High

458793

CSK2B
Casein kinase II subunit beta

1

7

Small-scale

0.536

High

263508

MK38B
Mitogen-activated protein kinase p38b

1

5

Small-scale

0.501

High

458805

Q8T030
Mitogen-activated protein kinase

1

6

Small-scale

0.501

High

304015

O76521
Importin subunit alpha

1

14

Small-scale

0.479

High

458795

PP12
Serine/threonine-protein phosphatase alpha-2 isoform

1

7

Small-scale

0.479

High

458796

E75BB
Ecdysone-induced protein 75B, isoform B

1

20

Small-scale

0.479

High

458797

SGG
Protein kinase shaggy

1

3

Small-scale

0.479

High

458800

DOD
Putative peptidyl-prolyl cis-trans isomerase dodo

1

2

Small-scale

0.479

High

458801

KC1A
Casein kinase I isoform alpha

1

20

Small-scale

0.479

High

458804

Q7JWQ7
RE01730p

1

2

High-throughput

0.464

High

458811

DHB4
Peroxisomal multifunctional enzyme type 2

1

1

High-throughput

0.464

High

68158

A8DY79
Bruchpilot, isoform G

1

8

High-throughput

0.439

High

120087

M9PCA7
Sodium chloride cotransporter 69, isoform C

1

1

High-throughput

0.439

High

458808

SUR8
Leucine-rich repeat protein soc-2 homolog

1

3

Small-scale

0.437

High

458806

Q9VB55
Without children, isoform A

1

4

High-throughput

0.417

High

458810

Q9VTW8
GH27027p

1

1

High-throughput

0.417

High

458794

LSP1B
Larval serum protein 1 beta chain

1

0

High-throughput

0.265

Low

458798

GLT
Glutactin

1

0

High-throughput

0.265

Low

458803

CUA1
Adult cuticle protein 1

1

0

High-throughput

0.265

Low

458809

Q9VLX9
Uncharacterized protein, isoform B

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025