Interactor 1: CERS5 (Q8N5B7)
Ceramide synthase 5 (CerS5) (LAG1 longevity assurance homolog 5) (Sphingoid base N-palmitoyltransferase CERS5) (EC 2.3.1.291) (Sphingosine N-acyltransferase CERS5) (EC 2.3.1.24)
Gene: CERS5
Interactor 2: CERS2 (Q96G23)
Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (SP260) (Sphingosine N-acyltransferase CERS2) (EC 2.3.1.24) (Tumor metastasis-suppressor gene 1 protein) (Very-long-chain ceramide synthase CERS2) (EC 2.3.1.297)
Gene: CERS2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.33 | 1.00 | 0.575 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | unassigned3799 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Homeodomain~Homeodomain, TRAM_LAG1_CLN8~TRAM_LAG1_CLN8 |
| Common GO terms | GO:0003677 - DNA binding GO:0005789 - endoplasmic reticulum membrane GO:0030148 - sphingolipid biosynthetic process GO:0046513 - ceramide biosynthetic process GO:0050291 - sphingosine N-acyltransferase activity |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
