HitPredict

Interactor 1: SDCB1 (O00560)
Syntenin-1 (Melanoma differentiation-associated protein 9) (MDA-9) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18) (Scaffold protein Pbp1) (Syndecan-binding protein 1)
Gene: SDCBP

Interactor 2: GRM7 (Q14831)
Metabotropic glutamate receptor 7 (mGluR7)
Gene: GRM7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11891216
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007268 - chemical synaptic transmission GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 298 Hs			1 915
+	Rn
		723204 SDCB1_RAT (1-298): 2.61e-101: 300: 89.33		GRM7_RAT (1-915): 0: 1002: 99.34
+	Rn
		680334 SDCB1_RAT (1-298): 2.61e-101: 300: 89.33		GRM4_RAT (28-915): 0: 916: 70.11
+	Hs
		132861 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		GRM3_HUMAN (2-896): 0: 803: 43.23
+	Rn
		680332 SDCB1_RAT (1-298): 2.61e-101: 300: 89.33		GRM3_RAT (2-896): 0: 806: 42.24
+	Rn
		722956 SDCB1_RAT (1-298): 2.61e-101: 300: 89.33		GRM6_RAT (55-868): 0: 800: 68.09
+	Mm
		1143332 DLG4_MOUSE (193-286): 2.27e-16: 81.4: 24.75		GRM7_MOUSE (1-915): 0: 1004: 99.45
+	Hs
		132856 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		GRM2_HUMAN (28-896): 0: 774: 43.34
+	Rn
		680333 GRIP1_RAT (101-269): 4.58e-12: 68.6: 20.60		GRM4_RAT (28-915): 0: 916: 70.11
+	Mm
		1143542 DLG4_MOUSE (193-286): 2.27e-16: 81.4: 24.75		GRM3_MOUSE (2-896): 0: 807: 42.35
+	Rn
		680329 GRIP1_RAT (101-269): 4.58e-12: 68.6: 20.60		GRM3_RAT (2-896): 0: 806: 42.24
+	Rn
		722955 GRIP1_RAT (101-269): 4.58e-12: 68.6: 20.60		GRM6_RAT (55-868): 0: 800: 68.09
+	Ce
		101944 G1K0W3_CAEEL (104-269): 2.74e-14: 75.1: 25.00		GRM1_CAEEL (4-888): 0: 698: 36.67
+	Hs
		132839 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		GRIK2_HUMAN (4-653): 4.36e-107: 354: 14.10
+	Hs
		132760 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		GRIK1_HUMAN (12-653): 3.08e-94: 319: 14.78
+	Rn
		611608 SDCB1_RAT (1-298): 2.61e-101: 300: 89.33		GRIK1_RAT (12-653): 4.88e-92: 314: 14.49
+	Hs
		1022366 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		GRIK2_HUMAN (4-653): 4.36e-107: 354: 14.10
+	Hs
		942335 DLG4_HUMAN (193-286): 2.16e-16: 81.4: 24.75		GRIK2_HUMAN (4-653): 4.36e-107: 354: 14.10
+	Rn
		677766 DLG4_RAT (193-286): 2.16e-16: 81.4: 24.75		GRIK2_RAT (4-653): 2.58e-105: 349: 14.10
+	Mm
		761217 DLG4_MOUSE (193-286): 2.27e-16: 81.4: 24.75		GRIK2_MOUSE (4-653): 2.14e-105: 349: 14.10
+	Hs
		761199 DLG4_HUMAN (193-286): 2.16e-16: 81.4: 24.75		GRIK1_HUMAN (12-653): 3.08e-94: 319: 14.78