HitPredict

Interactor 1: RBNS5 (Q9H1K0)
Rabenosyn-5 (110 kDa protein) (FYVE finger-containing Rab5 effector protein rabenosyn-5) (RAB effector RBSN) (Zinc finger FYVE domain-containing protein 20)
Gene: RBSN

Interactor 2: EHD1 (Q9H4M9)
EH domain-containing protein 1 (PAST homolog 1) (hPAST1) (Testilin)
Gene: EHD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.722

Property	Details
Experiments	28514442, 33961781, 16251358, 15020713, 20329706
Identification Methods	affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0010008 - endosome membrane GO:0031267 - small GTPase binding GO:0031901 - early endosome membrane GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 784 Hs			1 534
+	Hs
		1328759 RBNS5_HUMAN (1-784): 0: 952: 100.00		EHD3_HUMAN (1-533): 0: 796: 86.87
+	Hs
		1328754 RBNS5_HUMAN (1-784): 0: 952: 100.00		EHD4_HUMAN (1-532): 0: 776: 74.95
+	Hs
		1328760 RBNS5_HUMAN (1-784): 0: 952: 100.00		EHD2_HUMAN (1-534): 0: 776: 70.50
+	Dm
		1250500 Q9VLS5_DROME (8-502): 1.83e-132: 404: 28.79		Q8T8W3_DROME (10-531): 0: 754: 69.58
+	Hs
		1302776 RUFY1_HUMAN (20-222): 1.91e-42: 167: 15.64		ITSN2_HUMAN (429-515): 1.53e-17: 88.5: 34.09