Interactor 1: SIR6 (Q8N6T7)
NAD-dependent protein deacylase sirtuin-6 (EC 2.3.1.-) (NAD-dependent protein deacetylase sirtuin-6) (EC 2.3.1.286) (Protein mono-ADP-ribosyltransferase sirtuin-6) (EC 2.4.2.-) (Regulatory protein SIR2 homolog 6) (hSIRT6) (SIR2-like protein 6)
Gene: SIRT6

Interactor 2: RX (Q9Y2V3)
Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein)
Gene: RAX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 0.60 0.515

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 355
Hs

1 346
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025