HitPredict

Interactor 1: BORG4 (Q9H3Q1)
Cdc42 effector protein 4 (Binder of Rho GTPases 4)
Gene: CDC42EP4

Interactor 2: RHOJ (Q9H4E5)
Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein)
Gene: RHOJ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PBD~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0008360 - regulation of cell shape
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 356 Hs			1 214
+	Hs
		894420 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78
+	Hs
		925610 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51
+	Hs
		900891 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		RHOA_HUMAN (23-214): 1.09e-80: 240: 47.92
+	Hs
		545611 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		RAC2_HUMAN (22-214): 1.98e-78: 235: 57.51
+	Hs
		951333 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		RHOG_HUMAN (20-214): 1.44e-78: 235: 50.26
+	Hs
		564682 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		RHOQ_HUMAN (22-213): 5.09e-77: 231: 79.49
+	Hs
		892591 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		RAC3_HUMAN (22-195): 2.97e-77: 231: 62.64
+	Hs
		915970 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		RHOB_HUMAN (23-214): 1.69e-76: 230: 48.44
+	Hs
		894571 BORG2_HUMAN (2-229): 1.35e-56: 186: 24.21		CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78
+	Hs
		893907 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78
+	Hs
		960657 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RHOJ_HUMAN (1-214): 2.19e-84: 250: 100.00
+	Hs
		925198 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51
+	Hs
		900382 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RHOA_HUMAN (23-214): 1.09e-80: 240: 47.92
+	Hs
		436256 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RHOC_HUMAN (23-214): 6.63e-79: 236: 48.44
+	Hs
		564729 BORG2_HUMAN (2-229): 1.35e-56: 186: 24.21		RHOQ_HUMAN (22-213): 5.09e-77: 231: 79.49
+	Hs
		545325 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RAC2_HUMAN (22-214): 1.98e-78: 235: 57.51
+	Hs
		950927 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RHOG_HUMAN (20-214): 1.44e-78: 235: 50.26
+	Hs
		564481 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RHOQ_HUMAN (22-213): 5.09e-77: 231: 79.49
+	Hs
		892320 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RAC3_HUMAN (22-195): 2.97e-77: 231: 62.64
+	Hs
		915611 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RHOB_HUMAN (23-214): 1.69e-76: 230: 48.44