Protein: DCO
Discs overgrown protein kinase (EC 2.7.11.1) (Protein double-time)

Gene: DCO
Organism: Drosophila melanogaster
Interactions: 22
UniProt ID: O76324

Gene Ontology (top 5):
GO:0001933 - negative regulation of protein phosphorylation
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

303769

CI
Transcriptional activator cubitus interruptus

2

3

Small-scale

0.800

High

303768

PER
Period circadian protein

14

20

Small-scale

0.760

High

303773

KC1A
Casein kinase I isoform alpha

2

17

High-throughput

0.737

High

303774

CLIFF
Madf and zinc finger protein 1

2

2

High-throughput

0.737

High

303770

FAT
Cadherin-related tumor suppressor

3

1

Small-scale

0.640

High

303782

BDBT
Protein Bride of doubletime

3

0

Small-scale

0.613

High

303778

Q8SX40
Nicknack

1

0

High-throughput

0.586

High

263800

CLOCK
Circadian locomoter output cycles protein kaput

2

9

Small-scale

0.584

High

95194

E1JIH4
Uncharacterized protein, isoform D

1

1

High-throughput

0.575

High

303772

POLO
Serine/threonine-protein kinase polo

1

18

High-throughput

0.575

High

303776

Q5U8V5
PAR-domain protein 1 zeta

1

6

Small-scale

0.561

High

303771

TIM
Protein timeless

2

0

Small-scale

0.559

High

303785

Q9VGU4
FI02822p

1

7

High-throughput

0.536

High

303775

Q24253
AP complex subunit beta

2

3

High-throughput

0.521

High

57330

DLISH
SH3 domain-containing protein Dlish

1

3

Small-scale

0.479

High

303779

Q9V3E9
RNA polymerase II-associated protein 3

1

10

Small-scale

0.479

High

303781

Q9VDE3
LD08669p

1

10

Small-scale

0.479

High

303783

Q9VF10
F-box and leucine-rich repeat protein 7

1

3

Small-scale

0.479

High

303784

Q9VF74
Uncharacterized protein, isoform F

1

4

High-throughput

0.445

High

303777

Q86BS3
Chromator, isoform A

1

0

High-throughput

0.426

High

303780

TRF42
Inactive non-canonical poly(A) RNA polymerase protein Trf4-2

1

0

High-throughput

0.265

Low

53362

A1Z7N9
Vang-like protein

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025