HitPredict

Interactor 1: BORG4 (Q9H3Q1)
Cdc42 effector protein 4 (Binder of Rho GTPases 4)
Gene: CDC42EP4

Interactor 2: RHOF (Q9HBH0)
Rho-related GTP-binding protein RhoF (Rho family GTPase Rif) (Rho in filopodia)
Gene: RHOF

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PBD~Ras
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 356 Hs			1 211
+	Hs
		120638 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		RHOD_HUMAN (5-198): 4.14e-90: 265: 52.06
+	Hs
		925610 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		RAC1_HUMAN (20-211): 9.06e-84: 248: 49.48
+	Hs
		545611 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		RAC2_HUMAN (20-211): 2.82e-79: 237: 49.48
+	Hs
		951333 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		RHOG_HUMAN (19-211): 4.47e-79: 236: 46.11
+	Hs
		900891 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		RHOA_HUMAN (21-211): 1.51e-78: 235: 48.69
+	Hs
		564682 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		RHOQ_HUMAN (14-209): 4.28e-77: 232: 46.43
+	Hs
		892591 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		RAC3_HUMAN (20-193): 1.33e-77: 232: 50.58
+	Hs
		894420 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		CDC42_HUMAN (19-211): 1.19e-77: 232: 44.04
+	Hs
		915970 BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00		RHOB_HUMAN (21-200): 2.02e-58: 184: 48.89
+	Hs
		120391 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RHOD_HUMAN (5-198): 4.14e-90: 265: 52.06
+	Hs
		925198 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RAC1_HUMAN (20-211): 9.06e-84: 248: 49.48
+	Hs
		545325 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RAC2_HUMAN (20-211): 2.82e-79: 237: 49.48
+	Hs
		564729 BORG2_HUMAN (2-229): 1.35e-56: 186: 24.21		RHOQ_HUMAN (14-209): 4.28e-77: 232: 46.43
+	Hs
		894571 BORG2_HUMAN (2-229): 1.35e-56: 186: 24.21		CDC42_HUMAN (19-211): 1.19e-77: 232: 44.04
+	Hs
		900382 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RHOA_HUMAN (21-211): 1.51e-78: 235: 48.69
+	Hs
		564481 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RHOQ_HUMAN (14-209): 4.28e-77: 232: 46.43
+	Hs
		892320 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RAC3_HUMAN (20-193): 1.33e-77: 232: 50.58
+	Hs
		893907 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		CDC42_HUMAN (19-211): 1.19e-77: 232: 44.04
+	Hs
		436256 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RHOC_HUMAN (21-211): 1.44e-76: 230: 49.22
+	Hs
		915611 BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16		RHOB_HUMAN (21-200): 2.02e-58: 184: 48.89