HitPredict

Interactor 1: KC1A (P48729)
Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)
Gene: CSNK1A1

Interactor 2: FA83B (Q5T0W9)
Protein FAM83B
Gene: FAM83B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.720

Property	Details
Experiments	27684187, 35271311, 32707033, 23455922, 29789297
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, protein kinase assay, pull down, tandem affinity purification
Interaction Type	physical association, association, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 337 Hs			1 1011
+	Hs
		1211699 KC1AL_HUMAN (1-335): 1.09e-118: 347: 91.05		FA83B_HUMAN (1-1011): 0: 1931: 100.00
+	Hs
		885804 KC1E_HUMAN (9-311): 2e-116: 344: 74.26		FA83B_HUMAN (1-1011): 0: 1931: 100.00
+	Hs
		1253903 KC1AL_HUMAN (1-335): 1.09e-118: 347: 91.05		FA83H_HUMAN (1-287): 1.06e-125: 412: 46.92
+	Hs
		876905 KC1A_HUMAN (1-337): 1.05e-117: 345: 100.00		FA83H_HUMAN (1-287): 1.06e-125: 412: 46.92
+	Hs
		885817 KC1E_HUMAN (9-311): 2e-116: 344: 74.26		FA83H_HUMAN (1-287): 1.06e-125: 412: 46.92
+	Hs
		64668 KC1AL_HUMAN (1-335): 1.09e-118: 347: 91.05		FA83G_HUMAN (13-280): 2e-119: 387: 35.76
+	Hs
		64655 KC1A_HUMAN (1-337): 1.05e-117: 345: 100.00		FA83G_HUMAN (13-280): 2e-119: 387: 35.76
+	Hs
		64657 KC1E_HUMAN (9-311): 2e-116: 344: 74.26		FA83G_HUMAN (13-280): 2e-119: 387: 35.76
+	Hs
		1330289 KC1AL_HUMAN (1-335): 1.09e-118: 347: 91.05		FA83F_HUMAN (13-280): 8.05e-113: 359: 35.74
+	Hs
		876936 KC1A_HUMAN (1-337): 1.05e-117: 345: 100.00		FA83F_HUMAN (13-280): 8.05e-113: 359: 35.74
+	Hs
		1178731 KC1AL_HUMAN (1-335): 1.09e-118: 347: 91.05		FA83E_HUMAN (4-281): 4.27e-109: 349: 34.03
+	Hs
		1289419 KC1AL_HUMAN (1-335): 1.09e-118: 347: 91.05		FA83A_HUMAN (4-280): 1.01e-109: 349: 34.72
+	Hs
		1330299 KC1AL_HUMAN (1-335): 1.09e-118: 347: 91.05		FA83D_HUMAN (14-280): 1.96e-107: 348: 37.37
+	Hs
		876877 KC1A_HUMAN (1-337): 1.05e-117: 345: 100.00		FA83E_HUMAN (4-281): 4.27e-109: 349: 34.03
+	Hs
		876920 KC1A_HUMAN (1-337): 1.05e-117: 345: 100.00		FA83A_HUMAN (4-280): 1.01e-109: 349: 34.72
+	Hs
		1330297 KC1AL_HUMAN (1-335): 1.09e-118: 347: 91.05		FA83C_HUMAN (24-280): 7.39e-105: 346: 41.13
+	Hs
		876999 KC1A_HUMAN (1-337): 1.05e-117: 345: 100.00		FA83D_HUMAN (14-280): 1.96e-107: 348: 37.37
+	Hs
		885794 KC1E_HUMAN (9-311): 2e-116: 344: 74.26		FA83E_HUMAN (4-281): 4.27e-109: 349: 34.03
+	Hs
		885826 KC1E_HUMAN (9-311): 2e-116: 344: 74.26		FA83A_HUMAN (4-280): 1.01e-109: 349: 34.72
+	Hs
		876977 KC1A_HUMAN (1-337): 1.05e-117: 345: 100.00		FA83C_HUMAN (24-280): 7.39e-105: 346: 41.13