HitPredict

Interactor 1: LEMD2 (Q8NC56)
LEM domain-containing protein 2 (hLEM2)
Gene: LEMD2

Interactor 2: ACHA9 (Q9UGM1)
Neuronal acetylcholine receptor subunit alpha-9 (Nicotinic acetylcholine receptor subunit alpha-9) (NACHR alpha-9)
Gene: CHRNA9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 503 Hs			1 479
+	Hs
		733710 LEMD2_HUMAN (1-503): 0: 732: 100.00		ACHA3_HUMAN (26-477): 0: 538: 34.62
+	Hs
		723245 LEMD2_HUMAN (1-503): 0: 732: 100.00		ACHB4_HUMAN (11-477): 5.87e-175: 502: 30.61
+	Hs
		1052794 LEMD2_HUMAN (1-503): 0: 732: 100.00		ACHB3_HUMAN (7-478): 8.05e-165: 475: 31.22
+	Hs
		539725 LEMD2_HUMAN (1-503): 0: 732: 100.00		ACHB_HUMAN (22-478): 5.9e-152: 444: 28.90
+	Hs
		388150 MAN1_HUMAN (199-500): 3.97e-153: 461: 37.05		ACHA_HUMAN (13-475): 1.47e-154: 449: 33.76
+	Hs
		539753 MAN1_HUMAN (199-500): 3.97e-153: 461: 37.05		ACHB_HUMAN (22-478): 5.9e-152: 444: 28.90
+	Hs
		851177 LEMD2_HUMAN (1-503): 0: 732: 100.00		ACHA4_HUMAN (354-477): 1.3e-23: 106: 19.36