HitPredict

Interactor 1: GCN2 (Q9HGN1)
eIF-2-alpha kinase GCN2 (Serine/threonine-protein kinase gcn2) (EC 2.7.11.1) (Serine/threonine-protein kinase ppk28)
Gene: GCN2

Interactor 2: GCN2 (Q9HGN1)
eIF-2-alpha kinase GCN2 (Serine/threonine-protein kinase gcn2) (EC 2.7.11.1) (Serine/threonine-protein kinase ppk28)
Gene: GCN2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 23671279
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HGTP_anticodon2~HGTP_anticodon2, Pkinase~Pkinase, RWD~RWD, tRNA-synt_His~tRNA-synt_His
Common GO terms GO:0000049 - tRNA binding
GO:0004694 - eukaryotic translation initiation factor 2alpha kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 11 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1576
Sp

1 1576
+ Sc
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
+ At
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024