HitPredict

Interactor 1: CNOT7 (Q9UIV1)
CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a)
Gene: CNOT7

Interactor 2: TNR6B (Q9UPQ9)
Trinucleotide repeat-containing gene 6B protein
Gene: TNRC6B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	29395067, 21981923
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0005829 - cytosol GO:0031047 - regulatory ncRNA-mediated gene silencing GO:0060213 - positive regulation of nuclear-transcribed mRNA poly(A) tail shortening GO:1900153 - positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 1833
+	Hs
		1459120 CNOT8_HUMAN (1-282): 6.32e-172: 478: 76.24		TNR6B_HUMAN (28-1833): 0: 1100: 100.00
+	Hs
		1336875 CNOT7_HUMAN (1-285): 0: 502: 100.00		TNR6A_HUMAN (2-1833): 0: 817: 35.29
+	Hs
		1336868 CNOT8_HUMAN (1-282): 6.32e-172: 478: 76.24		TNR6A_HUMAN (2-1833): 0: 817: 35.29
+	Hs
		1439108 CNOT7_HUMAN (1-285): 0: 502: 100.00		TNR6C_HUMAN (34-1830): 0: 689: 34.46
+	Hs
		1439105 CNOT8_HUMAN (1-282): 6.32e-172: 478: 76.24		TNR6C_HUMAN (34-1830): 0: 689: 34.46
+	Dm
		1344097 X2JCC3_DROME (2-256): 5.6e-145: 412: 68.87		GAWKY_DROME (615-1735): 1.55e-149: 500: 21.36