HitPredict

Interactor 1: Q9HTM0 (Q9HTM0)
guanosine-3',5'-bis(diphosphate) 3'-diphosphatase (EC 3.1.7.2)
Gene: spoT

Interactor 2: Q9HTM0 (Q9HTM0)
guanosine-3',5'-bis(diphosphate) 3'-diphosphatase (EC 3.1.7.2)
Gene: spoT

Species: Pseudomonas aeruginosa PAO1

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	18996989
Identification Methods	adenylate cyclase complementation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ACT_4~ACT_4, HD_4~HD_4, HD_4~RelA_SpoT, RelA_SpoT~RelA_SpoT, RelA_SpoT~TGS, TGS~TGS
Common GO terms	GO:0005886 - plasma membrane GO:0008728 - GTP diphosphokinase activity GO:0008893 - guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity GO:0015969 - guanosine tetraphosphate metabolic process GO:0015970 - guanosine tetraphosphate biosynthetic process and 1 others more... GO:0042594 - response to starvation
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 701 Pa			1 701
+	Ec
		469139 SPOT_ECOLI (1-701): 0: 918: 54.05		SPOT_ECOLI (1-701): 0: 918: 54.05
+	Bs
		222274 RELA_BACSU (4-701): 0: 874: 38.51		RELA_BACSU (4-701): 0: 874: 38.51
+	Pa
		1336929 Q9I524_PSEAE (2-701): 0: 813: 31.84		Q9I524_PSEAE (2-701): 0: 813: 31.84
+	Ec
		469131 RELA_ECOLI (49-699): 0: 779: 32.02		RELA_ECOLI (49-699): 0: 779: 32.02
+	Cj
		1006228 Q0P8Y4_CAMJE (19-699): 0: 702: 30.37		Q0P8Y4_CAMJE (19-699): 0: 702: 30.37
+	Hp
		190617 O25466_HELPY (23-675): 0: 675: 29.03		O25466_HELPY (23-675): 0: 675: 29.03
+	Dm
		1361318 MESH1_DROME (25-152): 8.75e-38: 140: 36.36		MESH1_DROME (25-152): 8.75e-38: 140: 36.36
+	Ss
		937300 P72810_SYNY3 (25-149): 6.17e-35: 133: 33.59		P72810_SYNY3 (25-149): 6.17e-35: 133: 33.59