HitPredict

Interactor 1: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Interactor 2: LSM2 (Q9Y333)
U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5)
Gene: LSM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 783 Hs			1 95
+	Hs
		911976 DDX21_HUMAN (1-783): 0: 543: 100.00		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43
+	Hs
		911887 DDX42_HUMAN (2-757): 4.87e-137: 430: 20.41		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43
+	Sc
		624214 DBP1_YEAST (20-570): 1.18e-130: 403: 26.64		LSM2_YEAST (1-95): 2.94e-31: 106: 63.16
+	Hs
		133961 DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43
+	Hs
		571387 DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43
+	Zm
		39363 A0A1D6MWD6_MAIZE (193-563): 2.85e-89: 295: 41.78		B6UER1_MAIZE (1-90): 1.11e-34: 115: 73.33
+	Hs
		757541 IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23		SMD1_HUMAN (1-95): 6.66e-29: 101: 28.42
+	Sc
		415988 DED1_YEAST (196-541): 2.98e-56: 205: 37.98		LSM4_YEAST (1-83): 6.73e-22: 85.7: 22.83
+	Hs
		757543 IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23		SMD3_HUMAN (2-88): 6.44e-24: 89.6: 20.69
+	Hs
		757540 IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23		RUXF_HUMAN (3-71): 2.45e-23: 86.9: 31.43