HitPredict

Interactor 1: SNTG1 (Q9NSN8)
Gamma-1-syntrophin (G1SYN) (Syntrophin-4) (SYN4)
Gene: SNTG1

Interactor 2: DTNA (Q9Y4J8)
Dystrobrevin alpha (DTN-A) (Alpha-dystrobrevin) (Dystrophin-related protein 3)
Gene: DTNA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.626

Property	Details
Experiments	10747910, 33961781
Identification Methods	pull down, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 517 Hs			1 743
+	Mm
		1267816 SNTG1_MOUSE (1-498): 2.44e-168: 487: 94.58		DTNA_MOUSE (1-743): 0: 876: 94.93
+	Hs
		1348324 SNTG2_HUMAN (3-501): 4.64e-143: 423: 48.94		DTNA_HUMAN (1-743): 0: 900: 100.00
+	Mm
		1267814 SNTG2_MOUSE (3-501): 1.71e-146: 432: 50.68		DTNA_MOUSE (1-743): 0: 876: 94.93
+	Mm
		251086 SNTG1_MOUSE (1-498): 2.44e-168: 487: 94.58		DTNB_MOUSE (1-679): 0: 720: 68.93
+	Hs
		246499 SNTG1_HUMAN (1-517): 4.42e-169: 489: 100.00		DTNB_HUMAN (1-637): 0: 672: 70.81
+	Mm
		251085 SNTG2_MOUSE (3-501): 1.71e-146: 432: 50.68		DTNB_MOUSE (1-679): 0: 720: 68.93
+	Hs
		246500 SNTG2_HUMAN (3-501): 4.64e-143: 423: 48.94		DTNB_HUMAN (1-637): 0: 672: 70.81
+	Mm
		251082 SNTB2_MOUSE (15-490): 2.55e-121: 367: 22.52		DTNB_MOUSE (1-679): 0: 720: 68.93
+	Hs
		513902 SNTG1_HUMAN (1-517): 4.42e-169: 489: 100.00		DMD_HUMAN (14-646): 8.85e-170: 543: 25.65
+	Mm
		513809 SNTG1_MOUSE (1-498): 2.44e-168: 487: 94.58		DMD_MOUSE (14-658): 7.81e-170: 544: 25.49
+	Hs
		809186 SNTG1_HUMAN (1-517): 4.42e-169: 489: 100.00		UTRN_HUMAN (14-655): 4.26e-164: 527: 23.82
+	Mm
		513808 SNTG2_MOUSE (3-501): 1.71e-146: 432: 50.68		DMD_MOUSE (14-658): 7.81e-170: 544: 25.49
+	Mm
		985507 SNTG1_MOUSE (1-498): 2.44e-168: 487: 94.58		DRP2_MOUSE (14-647): 1.13e-158: 486: 22.70
+	Dm
		53635 A1ZAH3_DROME (9-497): 3.56e-135: 403: 38.59		A1Z904_DROME (1-641): 0: 567: 43.45
+	Hs
		513904 SNTG2_HUMAN (3-501): 4.64e-143: 423: 48.94		DMD_HUMAN (14-646): 8.85e-170: 543: 25.65
+	Dm
		1001116 Q8SX22_DROME (9-497): 3.04e-135: 403: 38.59		Q0E9B2_DROME (10-641): 0: 553: 43.44
+	Hs
		809188 SNTG2_HUMAN (3-501): 4.64e-143: 423: 48.94		UTRN_HUMAN (14-655): 4.26e-164: 527: 23.82
+	Mm
		985506 SNTG2_MOUSE (3-501): 1.71e-146: 432: 50.68		DRP2_MOUSE (14-647): 1.13e-158: 486: 22.70
+	Mm
		513793 SNTB2_MOUSE (15-490): 2.55e-121: 367: 22.52		DMD_MOUSE (14-658): 7.81e-170: 544: 25.49
+	Ce
		1140046 Q5WRR6_CAEEL (13-504): 1.11e-125: 378: 32.15		DMD_CAEEL (23-575): 6.15e-128: 422: 22.74