HitPredict

Interactor 1: FGOP2 (Q9NVK5)
FGFR1 oncogene partner 2
Gene: FGFR1OP2

Interactor 2: STK24 (Q9Y6E0)
Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]
Gene: STK24

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	26496610, 18782753, 32707033, 23455922
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 253 Hs			1 443
+	Hs
		72977 FGOP2_HUMAN (1-253): 2.35e-93: 276: 100.00		B4DR80_HUMAN (23-443): 1.38e-139: 407: 94.77
+	Hs
		1240585 FGOP2_HUMAN (1-253): 2.35e-93: 276: 100.00		Q8NBY1_HUMAN (12-438): 1.22e-137: 401: 64.40
+	Hs
		131613 FGOP2_HUMAN (1-253): 2.35e-93: 276: 100.00		STK25_HUMAN (24-434): 3.42e-136: 399: 72.26
+	Hs
		1346705 FGOP2_HUMAN (1-253): 2.35e-93: 276: 100.00		STK26_HUMAN (12-439): 6.21e-135: 395: 67.76
+	Hs
		1023126 FGOP2_HUMAN (1-253): 2.35e-93: 276: 100.00		STK4_HUMAN (27-315): 5.08e-129: 383: 52.22
+	Hs
		1027445 FGOP2_HUMAN (1-253): 2.35e-93: 276: 100.00		STK3_HUMAN (27-311): 8.23e-128: 380: 53.98
+	Hs
		1310721 SIKE1_HUMAN (1-238): 2.85e-56: 180: 43.50		STK24_HUMAN (1-443): 6.47e-163: 468: 100.00
+	Hs
		72975 SIKE1_HUMAN (1-238): 2.85e-56: 180: 43.50		B4DR80_HUMAN (23-443): 1.38e-139: 407: 94.77
+	Hs
		131600 SIKE1_HUMAN (1-238): 2.85e-56: 180: 43.50		STK25_HUMAN (24-434): 3.42e-136: 399: 72.26
+	Hs
		1310712 SIKE1_HUMAN (1-238): 2.85e-56: 180: 43.50		STK26_HUMAN (12-439): 6.21e-135: 395: 67.76
+	Dm
		1249843 FGOP2_DROME (4-223): 3.08e-53: 176: 27.73		HIPPO_DROME (27-361): 4.97e-120: 366: 45.43
+	Hs
		1346707 FGOP2_HUMAN (1-253): 2.35e-93: 276: 100.00		TNIK_HUMAN (31-316): 7.58e-72: 248: 44.70
+	Hs
		1310716 SIKE1_HUMAN (1-238): 2.85e-56: 180: 43.50		TNIK_HUMAN (31-316): 7.58e-72: 248: 44.70