HitPredict

Interactor 1: KLH28 (Q9NXS3)
Kelch-like protein 28 (BTB/POZ domain-containing protein 5)
Gene: KLHL28

Interactor 2: IPP (Q9Y573)
Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27)
Gene: IPP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BACK~BTB, BTB~BTB, Kelch_1~Kelch_1
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 571 Hs			1 584
+	Hs
		1348052 KLH28_HUMAN (1-571): 8.69e-177: 513: 100.00		KLHL9_HUMAN (4-584): 2.45e-149: 445: 25.68
+	Hs
		1348053 KLH28_HUMAN (1-571): 8.69e-177: 513: 100.00		KLH13_HUMAN (4-584): 1.47e-148: 444: 24.32
+	Hs
		1355221 KLHL3_HUMAN (14-571): 2.26e-163: 479: 37.88		KLHL3_HUMAN (16-584): 3.18e-161: 474: 33.45
+	Hs
		1164628 KLH28_HUMAN (1-571): 8.69e-177: 513: 100.00		KLH24_HUMAN (1-584): 1.87e-144: 432: 26.41
+	Hs
		1121499 KLH28_HUMAN (1-571): 8.69e-177: 513: 100.00		KLH26_HUMAN (2-582): 3.26e-134: 406: 26.32
+	Dm
		1181839 Q7KSF5_DROME (10-571): 3.22e-156: 467: 33.04		Q7KSF5_DROME (12-584): 1.23e-145: 441: 32.76
+	Hs
		1121506 KLHL3_HUMAN (14-571): 2.26e-163: 479: 37.88		KLH26_HUMAN (2-582): 3.26e-134: 406: 26.32
+	Hs
		307183 KLHL2_HUMAN (2-571): 2.85e-155: 459: 36.40		KLH26_HUMAN (2-582): 3.26e-134: 406: 26.32
+	Hs
		307227 KLHL3_HUMAN (14-571): 2.26e-163: 479: 37.88		KLHL2_HUMAN (123-484): 4.64e-48: 178: 21.10
+	Hs
		1049352 KLHL3_HUMAN (14-571): 2.26e-163: 479: 37.88		KEAP1_HUMAN (388-584): 1.25e-44: 169: 31.00
+	Hs
		307188 KLH17_HUMAN (8-571): 2.36e-158: 468: 41.09		KLHL2_HUMAN (123-484): 4.64e-48: 178: 21.10
+	Hs
		307154 KLHL2_HUMAN (2-571): 2.85e-155: 459: 36.40		KLHL2_HUMAN (123-484): 4.64e-48: 178: 21.10
+	Hs
		1120826 KLHL3_HUMAN (14-571): 2.26e-163: 479: 37.88		KLH12_HUMAN (9-438): 5.29e-40: 155: 18.14
+	Hs
		307172 KLHL2_HUMAN (2-571): 2.85e-155: 459: 36.40		KEAP1_HUMAN (388-584): 1.25e-44: 169: 31.00
+	Hs
		1120768 KLH17_HUMAN (8-571): 2.36e-158: 468: 41.09		KLH12_HUMAN (9-438): 5.29e-40: 155: 18.14
+	Hs
		307182 KLHL2_HUMAN (2-571): 2.85e-155: 459: 36.40		KLH12_HUMAN (9-438): 5.29e-40: 155: 18.14
+	Hs
		1164602 KLHL3_HUMAN (14-571): 2.26e-163: 479: 37.88		KLH17_HUMAN (275-436): 5.45e-32: 133: 28.40
+	Mm
		1164599 KLH17_MOUSE (8-571): 2.63e-158: 468: 41.27		KLH17_MOUSE (275-436): 5.39e-32: 133: 28.40
+	Hs
		1348055 KLH28_HUMAN (1-571): 8.69e-177: 513: 100.00		KLH21_HUMAN (339-584): 2.35e-13: 74.7: 24.80