Protein: AT133
Polyamine-transporting ATPase 13A3 (ATPase family homolog up-regulated in senescence cells 1) (Putrescine transporting ATPase) (EC 7.6.2.16)

Gene: AT133, ATP13A3
Organism: Homo sapiens
Interactions: 172
UniProt ID: Q9H7F0

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0006874 - intracellular calcium ion homeostasis
GO:0015203 - polyamine transmembrane transporter activity
GO:0015594 - ABC-type putrescine transporter activity
GO:0015662 - P-type ion transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

270686

ATP9A
Probable phospholipid-transporting ATPase IIA

1

13

High-throughput

0.691

High

127395

LEG8
Galectin-8

3

13

High-throughput

0.667

High

609806

LEG3
Galectin-3

3

13

High-throughput

0.667

High

1316379

AGRG5
Adhesion G-protein coupled receptor G5

3

4

High-throughput

0.662

High

1239049

NIPA3
Magnesium transporter NIPA3

3

9

High-throughput

0.643

High

1248494

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

2

2

High-throughput

0.628

High

1292024

TPRA1
Transmembrane protein adipocyte-associated 1

2

2

High-throughput

0.628

High

341676

EYA4
Protein phosphatase EYA4

1

3

High-throughput

0.618

High

125613

LEG9
Galectin-9

3

13

High-throughput

0.609

High

154884

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

3

9

High-throughput

0.609

High

1291899

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

3

20

High-throughput

0.609

High

1147852

DHC24
Delta(24)-sterol reductase

2

4

High-throughput

0.601

High

1348057

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

2

6

High-throughput

0.601

High

1435763

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

2

8

High-throughput

0.601

High

375959

RASK
GTPase KRas

2

18

High-throughput

0.584

High

978310

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

219370

B4GA1
Beta-1,4-glucuronyltransferase 1

2

0

High-throughput

0.576

High

406929

MAS
Proto-oncogene Mas

2

20

High-throughput

0.574

High

1435767

C5AR2
C5a anaphylatoxin chemotactic receptor 2

2

20

High-throughput

0.574

High

1101663

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

20

High-throughput

0.549

High

1430952

UN93B
Protein unc-93 homolog B1

2

4

High-throughput

0.549

High

1435765

GPC5B
G-protein coupled receptor family C group 5 member B

2

2

High-throughput

0.549

High

180051

BET1
BET1 homolog

1

2

High-throughput

0.536

High

182775

GP182
G-protein coupled receptor 182

1

20

High-throughput

0.536

High

231013

TYOBP
TYRO protein tyrosine kinase-binding protein

1

4

High-throughput

0.536

High

248629

FADS1
Acyl-CoA

1

4

High-throughput

0.536

High

316568

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

2

High-throughput

0.536

High

349571

TSN15
Tetraspanin-15

1

19

High-throughput

0.536

High

547339

CP19A
Aromatase

1

2

High-throughput

0.536

High

669071

FPR2
N-formyl peptide receptor 2

1

20

High-throughput

0.536

High

719845

V2R
Vasopressin V2 receptor

1

20

High-throughput

0.536

High

723262

ACHB4
Neuronal acetylcholine receptor subunit beta-4

1

4

High-throughput

0.536

High

1070181

NTCP7
Sodium/bile acid cotransporter 7

1

1

High-throughput

0.536

High

1179682

D19L1
Protein C-mannosyl-transferase DPY19L1

1

2

High-throughput

0.536

High

1242935

S39A4
Zinc transporter ZIP4

1

5

High-throughput

0.536

High

1307555

ZDH13
Palmitoyltransferase ZDHHC13

1

4

High-throughput

0.536

High

1350008

SPPL3
Signal peptide peptidase-like 3

1

8

High-throughput

0.536

High

1350072

SPP2B
Signal peptide peptidase-like 2B

1

8

High-throughput

0.536

High

1398479

TLCD4
TLC domain-containing protein 4

1

1

High-throughput

0.536

High

1429286

S22A4
Solute carrier family 22 member 4

1

11

High-throughput

0.536

High

1435758

B3GA2
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2

1

2

High-throughput

0.536

High

1435759

TMM9B
Transmembrane protein 9B

1

6

High-throughput

0.536

High

1435761

PXMP2
Peroxisomal membrane protein 2

1

2

High-throughput

0.536

High

1435770

P2RX2
P2X purinoceptor 2

1

3

High-throughput

0.536

High

1435774

ENTP4
Ectonucleoside triphosphate diphosphohydrolase 4

1

10

High-throughput

0.536

High

1435780

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

3

High-throughput

0.536

High

1435781

LHPL6
LHFPL tetraspan subfamily member 6 protein

1

2

High-throughput

0.536

High

1313842

S15A3
Solute carrier family 15 member 3

2

9

High-throughput

0.521

High

344492

STR3N
STARD3 N-terminal-like protein

1

0

High-throughput

0.513

High

1388191

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.513

High

133314

P2Y10
Putative P2Y purinoceptor 10

1

20

High-throughput

0.489

High

139318

UPK2
Uroplakin-2

1

3

High-throughput

0.489

High

166046

FFAR1
Free fatty acid receptor 1

1

20

High-throughput

0.489

High

184228

RER1
Protein RER1

1

3

High-throughput

0.489

High

221476

OX2R
Orexin receptor type 2

1

19

High-throughput

0.489

High

248508

O10H2
Olfactory receptor 10H2

1

3

High-throughput

0.489

High

252720

TSN3
Tetraspanin-3

1

17

High-throughput

0.489

High

253904

TPST2
Protein-tyrosine sulfotransferase 2

1

6

High-throughput

0.489

High

286788

SKAP2
Src kinase-associated phosphoprotein 2

1

8

High-throughput

0.489

High

348738

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

3

High-throughput

0.489

High

351967

S1PR4
Sphingosine 1-phosphate receptor 4

1

20

High-throughput

0.489

High

462808

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

2

High-throughput

0.489

High

575704

GPIX
Platelet glycoprotein IX

1

12

High-throughput

0.489

High

640470

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

20

High-throughput

0.489

High

833872

P2RY2
P2Y purinoceptor 2

1

20

High-throughput

0.489

High

835392

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

11

High-throughput

0.489

High

907059

CCR6
C-C chemokine receptor type 6

1

20

High-throughput

0.489

High

936125

PAR2
Proteinase-activated receptor 2

1

20

High-throughput

0.489

High

1098942

KLRD1
Natural killer cells antigen CD94

1

12

High-throughput

0.489

High

1126366

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

3

High-throughput

0.489

High

1142180

P2RY6
P2Y purinoceptor 6

1

20

High-throughput

0.489

High

1185363

LEG9B
Galectin-9B

1

13

High-throughput

0.489

High

1203797

TTMP
TPA-induced transmembrane protein

1

4

High-throughput

0.489

High

1251313

HACD2
Very-long-chain

1

5

High-throughput

0.489

High

1322214

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

1

High-throughput

0.489

High

1329477

KTAP2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2

1

1

High-throughput

0.489

High

1333422

S43A3
Equilibrative nucleobase transporter 1

1

2

High-throughput

0.489

High

1337029

T161B
Transmembrane protein 161B

1

2

High-throughput

0.489

High

1350890

HUMMR
Protein MGARP

1

2

High-throughput

0.489

High

1361310

CTR3
Cationic amino acid transporter 3

1

5

High-throughput

0.489

High

1361363

BRI3B
BRI3-binding protein

1

1

High-throughput

0.489

High

1382724

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

1

High-throughput

0.489

High

1387812

LEG12
Galectin-12

1

13

High-throughput

0.489

High

1392301

ZDH12
Palmitoyltransferase ZDHHC12

1

3

High-throughput

0.489

High

1399615

OPALI
Opalin

1

5

High-throughput

0.489

High

1412861

YIPF4
Protein YIPF4

1

2

High-throughput

0.489

High

1428235

GPR88
G protein-coupled receptor 88

1

2

High-throughput

0.489

High

1435753

WDR41
WD repeat-containing protein 41

1

6

High-throughput

0.489

High

1435754

ELOV3
Very long chain fatty acid elongase 3

1

6

High-throughput

0.489

High

1435756

GPR35
G-protein coupled receptor 35

1

20

High-throughput

0.489

High

1435757

JPH1
Junctophilin-1

1

2

High-throughput

0.489

High

1435762

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

1

8

High-throughput

0.489

High

1435764

GP173
Probable G-protein coupled receptor 173

1

12

High-throughput

0.489

High

1435766

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

6

High-throughput

0.489

High

1435769

HCST
Hematopoietic cell signal transducer

1

2

High-throughput

0.489

High

1435776

GPR55
G-protein coupled receptor 55

1

20

High-throughput

0.489

High

1435778

TMED5
Transmembrane emp24 domain-containing protein 5

1

11

High-throughput

0.489

High

1435779

GPR45
Probable G-protein coupled receptor 45

1

20

High-throughput

0.489

High

1435782

SPCS1
Signal peptidase complex subunit 1

1

1

High-throughput

0.489

High

189845

STX7
Syntaxin-7

1

6

High-throughput

0.479

High

327452

ZFPL1
Zinc finger protein-like 1

1

3

High-throughput

0.479

High

463773

LYN
Tyrosine-protein kinase Lyn

1

4

High-throughput

0.479

High

540679

LAMP1
Lysosome-associated membrane glycoprotein 1

1

12

High-throughput

0.479

High

562399

LAMP2
Lysosome-associated membrane glycoprotein 2

1

12

High-throughput

0.479

High

630974

RAB4A
Ras-related protein Rab-4A

1

10

High-throughput

0.479

High

631481

RAB5A
Ras-related protein Rab-5A

1

12

High-throughput

0.479

High

901045

RAB5C
Ras-related protein Rab-5C

1

12

High-throughput

0.479

High

955602

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

975248

ARF6
ADP-ribosylation factor 6

1

7

High-throughput

0.479

High

976566

RB11A
Ras-related protein Rab-11A

1

8

High-throughput

0.479

High

988713

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

1145114

RAB35
Ras-related protein Rab-35

1

8

High-throughput

0.479

High

1233487

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.479

High

1435768

ANFY1
Rabankyrin-5

1

1

High-throughput

0.479

High

1435773

LAMP3
Lysosome-associated membrane glycoprotein 3

1

12

High-throughput

0.479

High

104230

F5H1C8
Solute carrier family 15 member 3

1

9

High-throughput

0.445

High

256153

S19A2
Thiamine transporter 1

1

6

High-throughput

0.445

High

351254

MOT3
Monocarboxylate transporter 3

1

15

High-throughput

0.445

High

538806

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

12

High-throughput

0.445

High

641979

CD9
CD9 antigen

1

16

High-throughput

0.445

High

722620

CTR1
High affinity cationic amino acid transporter 1

1

7

High-throughput

0.445

High

870311

S6A12
Sodium- and chloride-dependent betaine transporter

1

5

High-throughput

0.445

High

1175899

TM241
UDP-N-acetylglucosamine transporter TMEM241

1

3

High-throughput

0.445

High

1236319

MFSD5
Molybdate-anion transporter

1

2

High-throughput

0.445

High

1242227

NPAL3
NIPA-like protein 3

1

9

High-throughput

0.445

High

1273805

NIPA1
Magnesium transporter NIPA1

1

9

High-throughput

0.445

High

1280815

S35E3
Solute carrier family 35 member E3

1

1

High-throughput

0.445

High

1312987

S35F2
Solute carrier family 35 member F2

1

8

High-throughput

0.445

High

1313994

S35F3
Solute carrier family 35 member F3

1

2

High-throughput

0.445

High

1346789

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

6

High-throughput

0.445

High

1357832

S35F5
Solute carrier family 35 member F5

1

7

High-throughput

0.445

High

1435775

S27A5
Long-chain fatty acid transport protein 5

1

6

High-throughput

0.445

High

126805

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.437

High

218786

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.437

High

374933

RASH
GTPase HRas

1

13

High-throughput

0.437

High

466465

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.437

High

506668

GPHRB
Golgi pH regulator B

1

5

High-throughput

0.437

High

581296

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.437

High

601448

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.437

High

604209

CXA1
Gap junction alpha-1 protein

1

9

High-throughput

0.437

High

715781

MARCS
Myristoylated alanine-rich C-kinase substrate

1

3

High-throughput

0.437

High

902075

RAB9A
Ras-related protein Rab-9A

1

14

High-throughput

0.437

High

953678

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.437

High

956494

RAB2A
Ras-related protein Rab-2A

1

10

High-throughput

0.437

High

962493

RHOA
Transforming protein RhoA

1

20

High-throughput

0.437

High

1015792

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.437

High

1255563

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.437

High

1322990

CXD3
Gap junction delta-3 protein

1

9

High-throughput

0.437

High

1381968

CK052
Uncharacterized protein C11orf52

1

2

High-throughput

0.437

High

1431748

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

6

High-throughput

0.437

High

1433510

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.437

High

1433901

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.437

High

1435755

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.437

High

85405

GPHRA
Golgi pH regulator A

1

5

High-throughput

0.407

High

886137

CXCR3
C-X-C chemokine receptor type 3

1

20

High-throughput

0.407

High

1211964

S35F1
Solute carrier family 35 member F1

1

13

High-throughput

0.407

High

1246113

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

12

High-throughput

0.407

High

1308975

S22A9
Organic anion transporter 7

1

11

High-throughput

0.407

High

1381027

S35B4
Nucleotide sugar transporter SLC35B4

1

7

High-throughput

0.407

High

1391463

S35A4
Probable UDP-sugar transporter protein SLC35A4

1

8

High-throughput

0.407

High

1404947

S1PR3
Sphingosine 1-phosphate receptor 3

1

20

High-throughput

0.407

High

1435760

S35C2
Solute carrier family 35 member C2

1

4

High-throughput

0.407

High

1435771

YLAT1
Y+L amino acid transporter 1

1

7

High-throughput

0.407

High

1435777

ZDHC9
Palmitoyltransferase ZDHHC9

1

1

High-throughput

0.407

High

1428158

YIPF3
Protein YIPF3

2

0

High-throughput

0.328

High

397708

NU4M
NADH-ubiquinone oxidoreductase chain 4

1

0

High-throughput

0.279

Low

1322838

ORML3
ORM1-like protein 3

1

0

High-throughput

0.279

Low

1349186

TLC3A
TLC domain-containing protein 3A

1

0

High-throughput

0.279

Low

1432892

PIGM
GPI alpha-1,4-mannosyltransferase I, catalytic subunit

1

0

High-throughput

0.279

Low

1435772

DOLK
Dolichol kinase

1

0

High-throughput

0.279

Low

1214128

DIK1A
Divergent protein kinase domain 1A

1

0

High-throughput

0.232

Low

1244114

TMM88
Transmembrane protein 88

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025