HitPredict

Interactor 1: ABI2 (Q9NYB9)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Interactor 2: BAIP2 (Q9UQB8)
BAR/IMD domain-containing adapter protein 2 (Brain-specific angiogenesis inhibitor 1-associated protein 2) (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53)
Gene: BAIAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SH3_1~SH3_2
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005912 - adherens junction GO:0008093 - cytoskeletal anchor activity GO:0030027 - lamellipodium and 1 others more... GO:0070064 - proline-rich region binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 513 Hs			1 552
+	Hs
		1224660 ABI1_HUMAN (1-513): 3.84e-97: 304: 61.00		BAIP2_HUMAN (1-552): 7.45e-143: 425: 100.00
+	Rn
		1151482 ABI1_RAT (1-513): 4.31e-96: 301: 59.45		BAIP2_RAT (1-529): 1.31e-130: 393: 94.72
+	Mm
		1208107 ABI1_MOUSE (1-513): 2.82e-100: 312: 60.04		PACN2_MOUSE (3-436): 4.92e-64: 218: 16.29
+	Ce
		1014645 Q10929_CAEEL (3-508): 2.34e-66: 223: 30.00		Q95Y95_CAEEL (3-478): 3.61e-42: 162: 11.56
+	Hs
		1356880 ASAP1_HUMAN (65-510): 8.77e-43: 165: 14.66		PACN2_HUMAN (3-436): 4.17e-62: 213: 15.61
+	Dm
		65063 Q9VDF4_DROME (253-508): 4.51e-34: 137: 20.15		A8DY50_DROME (19-373): 1.25e-65: 234: 16.67
+	Hs
		203262 SYNJ1_HUMAN (38-480): 2.57e-33: 137: 12.92		PACN2_HUMAN (3-436): 4.17e-62: 213: 15.61
+	Hs
		1166821 ABI3_HUMAN (262-507): 4.36e-17: 84.9: 23.17		BI2L2_HUMAN (5-529): 6.32e-81: 264: 24.74
+	Hs
		203224 SYNJ1_HUMAN (38-480): 2.57e-33: 137: 12.92		MYO1E_HUMAN (7-435): 3.08e-57: 208: 13.65
+	Hs
		1316001 ASAP1_HUMAN (65-510): 8.77e-43: 165: 14.66		PACN1_HUMAN (3-435): 1.16e-44: 165: 13.10
+	Hs
		1356556 ASAP1_HUMAN (65-510): 8.77e-43: 165: 14.66		PACN3_HUMAN (13-435): 1.11e-44: 165: 12.72
+	Hs
		200935 SRC8_HUMAN (271-507): 2.78e-32: 131: 17.84		MTSS1_HUMAN (19-501): 3.77e-52: 191: 18.18
+	Hs
		207845 ASAP1_HUMAN (65-510): 8.77e-43: 165: 14.66		PPIP1_HUMAN (33-435): 7.69e-42: 157: 16.19
+	Hs
		203251 SYNJ1_HUMAN (38-480): 2.57e-33: 137: 12.92		PACN1_HUMAN (3-435): 1.16e-44: 165: 13.10
+	Hs
		203260 SYNJ1_HUMAN (38-480): 2.57e-33: 137: 12.92		PACN3_HUMAN (13-435): 1.11e-44: 165: 12.72
+	Hs
		1045408 SRC8_HUMAN (271-507): 2.78e-32: 131: 17.84		SPTN1_HUMAN (3-442): 2.09e-42: 165: 11.85
+	Rn
		192738 SRBS2_RAT (293-509): 7.62e-17: 85.9: 14.35		SPTN1_RAT (3-442): 1.5e-42: 165: 11.64
+	Hs
		924555 GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93		SPTN1_HUMAN (3-442): 2.09e-42: 165: 11.85
+	Hs
		298006 ITSN2_HUMAN (289-512): 5.53e-14: 77.2: 15.63		FCSD2_HUMAN (36-512): 3.35e-41: 160: 12.94
+	Hs
		203228 SYNJ1_HUMAN (38-480): 2.57e-33: 137: 12.92		ITSN1_HUMAN (268-455): 5.42e-10: 64.5: 15.18