HitPredict

Interactor 1: TMOD3 (Q9NYL9)
Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod)
Gene: TMOD3

Interactor 2: LRRF2 (Q9Y608)
Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2)
Gene: LRRFIP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 352 Hs			1 721
+	Hs
		657568 TMOD1_HUMAN (3-348): 9.31e-129: 374: 62.14		LRRF2_HUMAN (1-721): 7.69e-104: 335: 100.00
+	Hs
		1349404 TMOD4_HUMAN (4-346): 1.14e-126: 368: 55.10		LRRF2_HUMAN (1-721): 7.69e-104: 335: 100.00
+	Hs
		1103967 TMOD3_HUMAN (1-352): 1.04e-142: 409: 100.00		LRRF1_HUMAN (280-458): 7.43e-52: 195: 56.35
+	Hs
		657503 TMOD1_HUMAN (3-348): 9.31e-129: 374: 62.14		LRRF1_HUMAN (280-458): 7.43e-52: 195: 56.35
+	Hs
		1103968 TMOD4_HUMAN (4-346): 1.14e-126: 368: 55.10		LRRF1_HUMAN (280-458): 7.43e-52: 195: 56.35
+	Dm
		221091 O46231_DROME (5-351): 7.16e-103: 308: 32.67		Q9VXN3_DROME (355-718): 2.45e-61: 212: 33.97
+	Hs
		1268101 TMOD3_HUMAN (1-352): 1.04e-142: 409: 100.00		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		725044 TMOD3_HUMAN (1-352): 1.04e-142: 409: 100.00		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Hs
		657527 TMOD1_HUMAN (3-348): 9.31e-129: 374: 62.14		DLG5_HUMAN (219-569): 1.09e-12: 74.1: 10.72
+	Hs
		657530 TMOD1_HUMAN (3-348): 9.31e-129: 374: 62.14		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		657463 TMOD1_HUMAN (3-348): 9.31e-129: 374: 62.14		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12